Drug resistance remains a major challenge in cancer treatment, necessitating the
development of novel strategies to overcome it. Protein arginine methyltransferases …

Iron is a crucial element required for the proper functioning of the body. For instance,
hemoglobin is the vital component in the blood that delivers oxygen to various parts of the …

Multicellular 3D culture and interaction with stromal components are considered essential
elements in establishing a 'more clinically relevant'tumor model. Matrix-embedded 3D …

Postoperative recurrence and metastasis have crucial roles in the poor prognosis of gastric
cancer patients. Previous studies have indicated that gastric cancer originates from cancer …

Integrating LC-MS/MS molecular networking and bioassay-guided fractionation enabled the
targeted isolation of a new and bioactive cyclic octapeptide, samoamide A (1), from a …

Simple Summary Dipeptidyl peptidase (DPP)-4 inhibitor is widely used for type 2 diabetes.
Although DPP-4/CD26 has been recognized as both a suppressor and inducer in tumor …

There is growing evidence of the presence of cancer stem cells in urothelial carcinoma.
Cancer stem cells have the ability to self‐renew and to differentiate into all cell types of the …

Resistance to chemotherapy agents is a major challenge infront of cancer patient treatment
and researchers. It is known that several factors, such as multidrug resistance proteins and …

The biological influence of antidiabetic drugs on cancer cells and diabetic cancer patients
has not yet been completely elucidated. We reported that a dipeptidyl peptidase (DPP)-4 …

Background: YS110 is a humanised IgG1 monoclonal antibody with high affinity to the CD26
antigen. YS110 demonstrated preclinical anti-tumour effects without significant side effects …