Opioid-associated out-of-hospital cardiac arrest: distinctive clinical features and implications for health care and public responses: a scientific statement from the …

C Dezfulian, AM Orkin, BA Maron, J Elmer, S Girotra… - Circulation, 2021 - Am Heart Assoc
Opioid overdose is the leading cause of death for Americans 25 to 64 years of age, and
opioid use disorder affects> 2 million Americans. The epidemiology of opioid-associated out …

Revive and refuse: Capacity, autonomy, and refusal of care after opioid overdose

KD Marshall, AR Derse, SG Weiner… - The American Journal …, 2024 - Taylor & Francis
Physicians generally recommend that patients resuscitated with naloxone after opioid
overdose stay in the emergency department for a period of observation in order to prevent …

Prevalence and charges of opioid-related visits to US emergency departments

JR Langabeer, AL Stotts, BJ Bobrow, HE Wang… - Drug and alcohol …, 2021 - Elsevier
Objective An overwhelming responsibility for responding to the opioid epidemic falls on
hospital emergency departments (ED). We sought to examine the overall prevalence rate …

Opioid overdose in the age of fentanyl: risk factor differences among subpopulations of overdose survivors

A Kline, D Mattern, N Cooperman, JM Williams… - International Journal of …, 2021 - Elsevier
Background Although fentanyl is the drug most frequently implicated in overdose deaths, the
association between overdose risk and attitudes and behaviors surrounding fentanyl in …

Slow‐sustained delivery of naloxone reduces typical naloxone‐induced precipitated opioid withdrawal effects in male morphine‐dependent mice

LA Lewter, MC Johnson, AC Treat… - Journal of …, 2022 - Wiley Online Library
Thousands of individuals die each year from opioid‐related overdoses. While naloxone
(Narcan®) is currently the most widely employed treatment to reverse opioid toxicity, high or …

Identifying high-risk areas for nonfatal opioid overdose: a spatial case-control study using EMS run data

J Pesarsick, M Gwilliam, O Adeniran, T Rudisill… - Annals of …, 2019 - Elsevier
Purpose The objective of our study was to incorporate stricter probable nonfatal opioid
overdose case criteria, and advanced epidemiologic approaches to more reliably detect …

Impact of the opioid epidemic

EJ Lavonas, C Dezfulian - Critical Care Clinics, 2020 - criticalcare.theclinics.com
Opioid misuse is endemic in the United States. In a 2017 survey, an estimated 11.4 million
Americans (4.2% of US persons aged 12 years or older) reported opioid misuse in the past …

[HTML][HTML] Stronger, longer, better opioid antagonists? Nalmefene is NOT a naloxone replacement

AF Infante, AT Elmes, RP Gimbar, SE Messmer… - International Journal of …, 2024 - Elsevier
The fatal overdose crisis claims nearly 200 lives daily in the United States (US). Evolutions
in the illicit drug supply, such as the addition of sedative adulterants and a shift to synthetic …

Prehospital naloxone and emergency department adverse events: a dose-dependent relationship

LM Maloney, T Alptunaer, G Coleman, S Ismael… - The Journal of …, 2020 - Elsevier
Background The purpose of this study was to evaluate prehospital and emergency
department (ED) interventions and outcomes of patients who received prehospital naloxone …

Prediction of naloxone dose in opioids toxicity based on machine learning techniques (artificial intelligence)

SA Mohtarami, B Mostafazadeh, S Shadnia… - DARU Journal of …, 2024 - Springer
Background Treatment management for opioid poisoning is critical and, at the same time,
requires specialized knowledge and skills. This study was designed to develop and …