Microfluidic nanoparticles for drug delivery
Nanoparticles (NPs) have attracted tremendous interest in drug delivery in the past decades.
Microfluidics offers a promising strategy for making NPs for drug delivery due to its capability …
Microfluidics offers a promising strategy for making NPs for drug delivery due to its capability …
[HTML][HTML] Mesoporous silica nanoparticles for drug and gene delivery
Y Zhou, G Quan, Q Wu, X Zhang, B Niu, B Wu… - … pharmaceutica sinica B, 2018 - Elsevier
Mesoporous silica nanoparticles (MSNs) are attracting increasing interest for potential
biomedical applications. With tailored mesoporous structure, huge surface area and pore …
biomedical applications. With tailored mesoporous structure, huge surface area and pore …
In vivo gene delivery mediated by non-viral vectors for cancer therapy
R Mohammadinejad, A Dehshahri… - Journal of Controlled …, 2020 - Elsevier
Gene therapy by expression constructs or down-regulation of certain genes has shown great
potential for the treatment of various diseases. The wide clinical application of nucleic acid …
potential for the treatment of various diseases. The wide clinical application of nucleic acid …
The potential of insects as alternative sources of chitin: An overview on the chemical method of extraction from various sources
NA Zainol Abidin, F Kormin, NA Zainol Abidin… - International Journal of …, 2020 - mdpi.com
Chitin, being the second most abundant biopolymer after cellulose, has been gaining
popularity since its initial discovery by Braconot in 1811. However, fundamental knowledge …
popularity since its initial discovery by Braconot in 1811. However, fundamental knowledge …
Nucleic acid therapeutics using polyplexes: a journey of 50 years (and beyond)
U Lächelt, E Wagner - Chemical reviews, 2015 - ACS Publications
Since the elucidation of the molecular structure of nucleic acids and understanding of their
role in encoding and translating genetic information into biological function, 1 the knowledge …
role in encoding and translating genetic information into biological function, 1 the knowledge …
Nanoparticle‐mediated double‐stranded RNA delivery system: A promising approach for sustainable pest management
S Yan, BY Ren, J Shen - Insect Science, 2021 - Wiley Online Library
RNA interference (RNAi) targeting lethal genes in insects has great potential for sustainable
crop protection. Compared with traditional double‐stranded (ds) RNA delivery systems …
crop protection. Compared with traditional double‐stranded (ds) RNA delivery systems …
Chitosan-based nanomaterials: A state-of-the-art review
This manuscript briefly reviews the extensive research as well as new developments on
chitosan based nanomaterials for various applications. Chitosan is a biocompatible and …
chitosan based nanomaterials for various applications. Chitosan is a biocompatible and …
[HTML][HTML] Polymeric delivery systems for nucleic acid therapeutics: Approaching the clinic
AIS van den Berg, CO Yun, RM Schiffelers… - Journal of Controlled …, 2021 - Elsevier
Gene therapy using nucleic acids has many clinical applications for the treatment of
diseases with a genetic origin as well as for the development of innovative vaccine …
diseases with a genetic origin as well as for the development of innovative vaccine …
The proton sponge hypothesis: Fable or fact?
LMP Vermeulen, SC De Smedt, K Remaut… - European Journal of …, 2018 - Elsevier
In non-viral gene therapy, cationic polymers and lipids are frequently used to encapsulate
macromolecular therapeutics into nanoparticles. During their journey to deliver the cargo to …
macromolecular therapeutics into nanoparticles. During their journey to deliver the cargo to …
Biomimetic delivery of signals for bone tissue engineering
Bone tissue engineering is an exciting approach to directly repair bone defects or engineer
bone tissue for transplantation. Biomaterials play a pivotal role in providing a template and …
bone tissue for transplantation. Biomaterials play a pivotal role in providing a template and …