A pragmatic guide to enrichment strategies for mass spectrometry–based glycoproteomics

NM Riley, CR Bertozzi, SJ Pitteri - Molecular & Cellular Proteomics, 2021 - ASBMB
Glycosylation is a prevalent, yet heterogeneous modification with a broad range of
implications in molecular biology. This heterogeneity precludes enrichment strategies that …

Advances in enrichment methods for mass spectrometry-based proteomics analysis of post-translational modifications

J Brandi, R Noberini, T Bonaldi, D Cecconi - Journal of Chromatography A, 2022 - Elsevier
Post-translational modifications (PTMs) occur during or after protein biosynthesis and
increase the functional diversity of proteome. They comprise phosphorylation, acetylation …

Proteomics of post-translational modifications in colorectal cancer: Discovery of new biomarkers

G Zhu, L Jin, W Sun, S Wang, N Liu - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
Colorectal cancer (CRC) is one of the costliest health problems and ranks second in cancer-
related mortality in developed countries. With the aid of proteomics, many protein …

Glycans as biomarkers in prostate cancer

E Scott, J Munkley - International journal of molecular sciences, 2019 - mdpi.com
Prostate cancer is the most commonly diagnosed malignancy in men, claiming over 350,000
lives worldwide annually. Current diagnosis relies on prostate-specific antigen (PSA) testing …

Recent advances in lectin-based affinity sorbents for protein glycosylation studies

A Goumenou, N Delaunay, V Pichon - Frontiers in Molecular …, 2021 - frontiersin.org
Glycosylation is one of the most significant post-translational modifications occurring to
proteins, since it affects some of their basic properties, such as their half-life or biological …

Current methods of post-translational modification analysis and their applications in blood cancers

K Dunphy, P Dowling, D Bazou, P O'Gorman - Cancers, 2021 - mdpi.com
Simple Summary This review discusses current techniques used to study post-translational
protein modifications (PTMs) and their contribution to blood cancer research. Blood cancer …

[HTML][HTML] Protein post-translational modifications: A key factor in colorectal cancer resistance mechanisms

B Bi, M Qiu, P Liu, Q Wang, Y Wen, Y Li, B Li… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Colorectal cancer (CRC) is one of the leading causes of cancer-related death. Despite
advances in treatment, drug resistance remains a critical impediment. Post-translational …

Intact glycopeptides identified by LC-MS/MS as biomarkers for response to chemotherapy of locally advanced cervical cancer

J Li, X Feng, C Zhu, Y Jiang, H Liu, W Feng… - Frontiers in …, 2023 - frontiersin.org
Objective For locally advanced cervical cancer (LACC), patients who respond to
chemotherapy have a potential survival advantage compared to nonresponsive patients …

Optimization of glycopeptide enrichment techniques for the identification of clinical biomarkers

S Onigbinde, CD Gutierrez Reyes… - Expert Review of …, 2024 - Taylor & Francis
Introduction The identification and characterization of glycopeptides through LC-MS/MS and
advanced enrichment techniques are crucial for advancing clinical glycoproteomics …

Fucosylation in urological cancers

K Fujita, K Hatano, M Hashimoto, E Tomiyama… - International journal of …, 2021 - mdpi.com
Fucosylation is an oligosaccharide modification that plays an important role in immune
response and malignancy, and specific fucosyltransferases (FUTs) catalyze the three types …