Protein synthesis in mammalian mitochondria produces 13 proteins that are essential
subunits of the oxidative phosphorylation complexes. This review provides a detailed outline …

Oxidative phosphorylation (OXPHOS) is the mechanism whereby ATP, the major energy
source for the cell, is produced by harnessing cellular respiration in the mitochondrion. This …

The mitochondrion is arguably the most complex organelle in the budding yeast cell
cytoplasm. It is essential for viability as well as respiratory growth. Its innermost aqueous …

The mitochondrial ATP synthase fuels eukaryotic cells with chemical energy. Here we report
the cryo-EM structure of a divergent ATP synthase dimer from mitochondria of Euglena …

The Letm1 (leucine zipper-, EF hand-containing transmembrane protein 1) gene encodes a
mitochondrial inner membrane protein, whose depletion severely perturbs mitochondrial Ca …

Mitochondria autophagy (mitophagy) is a process that selectively degrades mitochondria via
autophagy. Recently, there has been significant progress in the understanding of mitophagy …

Ion fluxes across the inner mitochondrial membrane control mitochondrial volume, energy
production, and apoptosis. TMBIM5, a highly conserved protein with homology to putative …

Mitoribosomes are specialized for the synthesis of hydrophobic membrane proteins
encoded by mtDNA, all essential for oxidative phosphorylation. Despite their linkage to …

Mitochondrial function is essential for life. Therefore, it is unsurprising that perturbations in
mitochondrial function have wide-ranging consequences in the cell. High-throughput …

LETM1 is a mitochondrial inner membrane protein that is required for maintaining the
mitochondrial morphology and cristae structures, and regulates mitochondrial ion …