Molecular pathogenesis and mechanisms of thyroid cancer

M Xing - Nature Reviews Cancer, 2013 - nature.com
Thyroid cancer is a common endocrine malignancy. There has been exciting progress in
understanding its molecular pathogenesis in recent years, as best exemplified by the …

Molecular genetics and diagnosis of thyroid cancer

YE Nikiforov, MN Nikiforova - Nature Reviews Endocrinology, 2011 - nature.com
Thyroid cancer is a common type of endocrine malignancy, and its incidence has been
steadily increasing in many regions of the world. Initiation and progression of thyroid cancer …

Integrated genomic characterization of papillary thyroid carcinoma

N Agrawal, R Akbani, BA Aksoy, A Ally, H Arachchi… - Cell, 2014 - cell.com
Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Here, we
describe the genomic landscape of 496 PTCs. We observed a low frequency of somatic …

Characterizing dedifferentiation of thyroid cancer by integrated analysis

H Luo, X Xia, GD Kim, Y Liu, Z Xue, L Zhang, Y Shu… - Science …, 2021 - science.org
Understanding of dedifferentiation, an indicator of poo prognosis for patients with thyroid
cancer, has been hampered by imprecise and incomplete characterization of its …

[PDF][PDF] Guidelines for the management of thyroid cancer.

P Perros, K Boelaert, S Colley, C Evans… - Clinical …, 2014 - rouxgroup.org.uk
Guidelines for the management of thyroid cancer Page 1 CLINICAL ENDOCRINOLOGY
VOLUME 81 SUPPLEMENT 1 JULY 2014 THE CLINICAL JOURNAL OF THE SOCIETY FOR …

BRAF Mutation in Papillary Thyroid Cancer: Pathogenic Role, Molecular Bases, and Clinical Implications

M Xing - Endocrine reviews, 2007 - academic.oup.com
In recent years, the T1799A B-type Raf kinase (BRAF) mutation in thyroid cancer has
received enthusiastic investigation, and significant progress has been made toward …

BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer

M Xing, WH Westra, RP Tufano, Y Cohen… - The Journal of …, 2005 - academic.oup.com
Context: Use of BRAF mutation in papillary thyroid cancer (PTC) has the potential to improve
risk stratification of this cancer. Objective: The objective of the study was to investigate the …

[HTML][HTML] Papillary thyroid cancer: genetic alterations and molecular biomarker investigations

MI Abdullah, SM Junit, KL Ng… - … journal of medical …, 2019 - ncbi.nlm.nih.gov
Papillary thyroid cancer (PTC) is the most prevalent form of malignancy among all cancers of
the thyroid. It is also one of the few cancers with a rapidly increasing incidence. PTC is …

MicroRNA expression profiling of thyroid tumors: biological significance and diagnostic utility

MN Nikiforova, GC Tseng, D Steward… - The Journal of …, 2008 - academic.oup.com
Objective: MicroRNA (miRNA) expression is deregulated in many types of human cancers.
We sought to investigate the expression patterns of miRNA in all major types of thyroid …

Correlation between genetic alterations and microscopic features, clinical manifestations, and prognostic characteristics of thyroid papillary carcinomas

AJ Adeniran, Z Zhu, M Gandhi… - The American journal …, 2006 - journals.lww.com
Papillary carcinoma is the most common type of thyroid malignancy. It has been recently
shown that these tumors commonly have one of three genetic alterations: BRAF point …