Abstract Narcolepsy type 1 (NT1) is a chronic sleep disorder resulting from the loss of a
small population of hypothalamic neurons that produce wake-promoting hypocretin (HCRT; …

Emulsion adjuvants such as MF59 and AS03 have been used for more than two decades as
key components of licensed vaccines, with over 100 million doses administered to diverse …

Purpose Narcolepsy type-1 (NT1) is a rare chronic neurological sleep disorder with
excessive daytime sleepiness (EDS) as usual first and cataplexy as pathognomonic …

Narcolepsy is a rare chronic neurological disorder characterized by an irresistible excessive
daytime sleepiness and cataplexy. The disease is considered to be the result of the selective …

Background and Objectives Recent studies fueled doubts as to whether all currently defined
central disorders of hypersomnolence are stable entities, especially narcolepsy type 2 and …

In the wake of the A/California/7/2009 H1N1 influenza pandemic vaccination campaigns in
2009-2010, an increased incidence of the chronic sleep-wake disorder narcolepsy was …

Abstract Study Objectives Increased incidence of narcolepsy was reported in children during
the 2009 H1N1 pandemic following Pandemrix, a H1N1 flu vaccine. A link with A (H1N1) …

Objective It is hypothesized that narcolepsy type 1 (NT1) develops in genetically susceptible
people who encounter environmental triggers leading to immune-mediated hypocretin-1 …

This study was aimed to evaluate the yearly incidence of pediatric narcolepsy prior to and
following the 2009 H1N1 pandemic and to evaluate seasonal patterns of narcolepsy onset …

Summary Narcolepsy type 1 (NT1) is a sleep-wake disorder in which people typically
experience excessive daytime sleepiness, cataplexy and other sleep-wake disturbances …