Diabetes has been recognized as an important risk factor for a variety of intracellular
bacterial infections, but research into the dysregulated immune mechanisms contributing to …

The dual burden of tuberculosis (TB) and diabetes has attracted much attention in the past
decade as diabetes prevalence has increased dramatically in countries already afflicted with …

The recent pandemic of COVID-19 has made abundantly clear that Type 2 diabetes (T2D)
increases the risk of more frequent and more severe viral infections. At the same time, pro …

Diabetes mellitus is a chronic, progressive, incompletely understood metabolic disorder
whose prevalence has been increasing steadily worldwide. Even though little attention has …

The spread of human immunodeficiency virus (HIV) infection within Africa led to marked
increases in numbers of cases of tuberculosis (TB), and although the epidemic peaked in …

Metabolic diseases are based on a dysregulated crosstalk between various cells such as
adipocytes, hepatocytes and immune cells. Generally, hormones and metabolites mediate …

Intervertebral disc degeneration (IVDD) is a major cause of low back pain. Diabetes mellitus
is a chronic inflammatory disease that may cause or aggravate IVDD; however, the …

Background The prevalence of type 2 diabetes (T2D) is increasing worldwide and creating a
significant burden on health systems, highlighting the need for the development of …

Obesity is characterised by a chronic state of low-grade inflammation in different tissues
including the vasculature. There is a causal link between adipose tissue (AT) inflammation …

Nutrients are required for growth and survival of all cells, but are also crucially involved in
cell fate determination of many cell types, including immune cells. There is a growing …