Consensus paper: towards a systems-level view of cerebellar function: the interplay between cerebellum, basal ganglia, and cortex

D Caligiore, G Pezzulo, G Baldassarre, AC Bostan… - The Cerebellum, 2017 - Springer
Despite increasing evidence suggesting the cerebellum works in concert with the cortex and
basal ganglia, the nature of the reciprocal interactions between these three brain regions …

Re-evaluating circuit mechanisms underlying pattern separation

NA Cayco-Gajic, RA Silver - Neuron, 2019 - cell.com
When animals interact with complex environments, their neural circuits must separate
overlapping patterns of activity that represent sensory and motor information. Pattern …

Optimal degrees of synaptic connectivity

A Litwin-Kumar, KD Harris, R Axel, H Sompolinsky… - Neuron, 2017 - cell.com
Synaptic connectivity varies widely across neuronal types. Cerebellar granule cells receive
five orders of magnitude fewer inputs than the Purkinje cells they innervate, and cerebellum …

Computational principles of supervised learning in the cerebellum

JL Raymond, JF Medina - Annual review of neuroscience, 2018 - annualreviews.org
Supervised learning plays a key role in the operation of many biological and artificial neural
networks. Analysis of the computations underlying supervised learning is facilitated by the …

Impact of perineuronal nets on electrophysiology of parvalbumin interneurons, principal neurons, and brain oscillations: a review

JC Wingert, BA Sorg - Frontiers in synaptic neuroscience, 2021 - frontiersin.org
Perineuronal nets (PNNs) are specialized extracellular matrix structures that surround
specific neurons in the brain and spinal cord, appear during critical periods of development …

Cerebellar granule cells acquire a widespread predictive feedback signal during motor learning

A Giovannucci, A Badura, B Deverett, F Najafi… - Nature …, 2017 - nature.com
Cerebellar granule cells, which constitute half the brain's neurons, supply Purkinje cells with
contextual information necessary for motor learning, but how they encode this information is …

Impaired tuning of neural ensembles and the pathophysiology of schizophrenia: a translational and computational neuroscience perspective

JH Krystal, A Anticevic, GJ Yang, G Dragoi… - Biological …, 2017 - Elsevier
The functional optimization of neural ensembles is central to human higher cognitive
functions. When the functions through which neural activity is tuned fail to develop or break …

Sparse activity of identified dentate granule cells during spatial exploration

M Diamantaki, M Frey, P Berens, P Preston-Ferrer… - Elife, 2016 - elifesciences.org
In the dentate gyrus–a key component of spatial memory circuits–granule cells (GCs) are
known to be morphologically diverse and to display heterogeneous activity profiles during …

Neural correlates of sparse coding and dimensionality reduction

M Beyeler, EL Rounds, KD Carlson, N Dutt… - PLoS computational …, 2019 - journals.plos.org
Supported by recent computational studies, there is increasing evidence that a wide range
of neuronal responses can be understood as an emergent property of nonnegative sparse …

Multimodal sensory integration in single cerebellar granule cells in vivo

T Ishikawa, M Shimuta, M Häusser - Elife, 2015 - elifesciences.org
The mammalian cerebellum is a highly multimodal structure, receiving inputs from multiple
sensory modalities and integrating them during complex sensorimotor coordination tasks …