Baicalin mediated regulation of key signaling pathways in cancer
Baicalin has been widely investigated against different types of malignancies both at the
cellular and molecular levels over the past few years. Due to its remarkable anti-proliferative …
cellular and molecular levels over the past few years. Due to its remarkable anti-proliferative …
An update on the anticancer activity of xanthone derivatives: A review
The annual number of cancer deaths continues increasing every day; thus, it is urgent to
search for and find active, selective, and efficient anticancer drugs as soon as possible …
search for and find active, selective, and efficient anticancer drugs as soon as possible …
Regiodivergent construction of medium-sized heterocycles from vinylethylene carbonates and allylidenemalononitriles
X Zhang, X Li, JL Li, QW Wang, WL Zou, YQ Liu… - Chemical …, 2020 - pubs.rsc.org
Medium-sized heterocycles exist in a broad spectrum of biologically active natural products
and medicinally important synthetic compounds. The construction of medium-sized rings …
and medicinally important synthetic compounds. The construction of medium-sized rings …
Isolation and Characterization of an Endophytic Fungus Colletotrichum coccodes Producing Tyrosol From Houttuynia cordata Thunb. Using ITS2 RNA Secondary …
An endophytic fungus isolated from healthy leaf tissues of Houttuynia cordata Thunb., an
ethnomedicinal plant of North East India, showed a considerable amount of antimicrobial …
ethnomedicinal plant of North East India, showed a considerable amount of antimicrobial …
A review of ligand-based virtual screening web tools and screening algorithms in large molecular databases in the age of big data
AJ Banegas-Luna, JP Cerón-Carrasco… - Future medicinal …, 2018 - Taylor & Francis
Virtual screening has become a widely used technique for helping in drug discovery
processes. The key to this success is its ability to aid in the identification of novel bioactive …
processes. The key to this success is its ability to aid in the identification of novel bioactive …
Suspect, nontarget screening, and toxicity prediction of per-and polyfluoroalkyl substances in the landfill leachate
C Feng, Y Lin, S Le, J Ji, Y Chen, G Wang… - Environmental …, 2024 - ACS Publications
Landfills are the final stage of urban wastes containing perfluoroalkyl and polyfluoroalkyl
substances (PFASs). PFASs in the landfill leachate may contaminate the surrounding …
substances (PFASs). PFASs in the landfill leachate may contaminate the surrounding …
3D-QSAR, Docking, ADME/Tox studies on Flavone analogs reveal anticancer activity through Tankyrase inhibition
Flavones are known as an inhibitor of tankyrase, a potential drug target of cancer. We here
expedited the use of different computational approaches and presented a fast, easy, cost …
expedited the use of different computational approaches and presented a fast, easy, cost …
Potential Inhibitors of Galactofuranosyltransferase 2 (GlfT2): Molecular Docking, 3D-QSAR, and In Silico ADMETox Studies
A strategy in the discovery of anti-tuberculosis (anti-TB) drug involves targeting the enzymes
involved in the biosynthesis of Mycobacterium tuberculosis'(Mtb) cell wall. One of these …
involved in the biosynthesis of Mycobacterium tuberculosis'(Mtb) cell wall. One of these …
ADMET profile and virtual screening of plant and microbial natural metabolites as SARS-CoV-2 S1 glycoprotein receptor binding domain and main protease inhibitors
In an attempt to search for selective inhibitors against the SARS-CoV-2 which caused
devastating of lives and livelihoods across the globe, 415 natural metabolites isolated from …
devastating of lives and livelihoods across the globe, 415 natural metabolites isolated from …
Novel trends, challenges and new perspectives for enamel repair and regeneration to treat dental defects
Dental enamel is the hardest tissue in the human body, providing external protection for the
tooth against masticatory forces, temperature changes and chemical stimuli. Once enamel is …
tooth against masticatory forces, temperature changes and chemical stimuli. Once enamel is …