Baicalin mediated regulation of key signaling pathways in cancer

S Singh, A Meena, S Luqman - Pharmacological research, 2021 - Elsevier
Baicalin has been widely investigated against different types of malignancies both at the
cellular and molecular levels over the past few years. Due to its remarkable anti-proliferative …

An update on the anticancer activity of xanthone derivatives: A review

YS Kurniawan, KTA Priyangga, Jumina, HD Pranowo… - Pharmaceuticals, 2021 - mdpi.com
The annual number of cancer deaths continues increasing every day; thus, it is urgent to
search for and find active, selective, and efficient anticancer drugs as soon as possible …

Regiodivergent construction of medium-sized heterocycles from vinylethylene carbonates and allylidenemalononitriles

X Zhang, X Li, JL Li, QW Wang, WL Zou, YQ Liu… - Chemical …, 2020 - pubs.rsc.org
Medium-sized heterocycles exist in a broad spectrum of biologically active natural products
and medicinally important synthetic compounds. The construction of medium-sized rings …

Isolation and Characterization of an Endophytic Fungus Colletotrichum coccodes Producing Tyrosol From Houttuynia cordata Thunb. Using ITS2 RNA Secondary …

R Talukdar, S Padhi, AK Rai, M Masi… - … in bioengineering and …, 2021 - frontiersin.org
An endophytic fungus isolated from healthy leaf tissues of Houttuynia cordata Thunb., an
ethnomedicinal plant of North East India, showed a considerable amount of antimicrobial …

A review of ligand-based virtual screening web tools and screening algorithms in large molecular databases in the age of big data

AJ Banegas-Luna, JP Cerón-Carrasco… - Future medicinal …, 2018 - Taylor & Francis
Virtual screening has become a widely used technique for helping in drug discovery
processes. The key to this success is its ability to aid in the identification of novel bioactive …

Suspect, nontarget screening, and toxicity prediction of per-and polyfluoroalkyl substances in the landfill leachate

C Feng, Y Lin, S Le, J Ji, Y Chen, G Wang… - Environmental …, 2024 - ACS Publications
Landfills are the final stage of urban wastes containing perfluoroalkyl and polyfluoroalkyl
substances (PFASs). PFASs in the landfill leachate may contaminate the surrounding …

3D-QSAR, Docking, ADME/Tox studies on Flavone analogs reveal anticancer activity through Tankyrase inhibition

S Alam, F Khan - Scientific reports, 2019 - nature.com
Flavones are known as an inhibitor of tankyrase, a potential drug target of cancer. We here
expedited the use of different computational approaches and presented a fast, easy, cost …

Potential Inhibitors of Galactofuranosyltransferase 2 (GlfT2): Molecular Docking, 3D-QSAR, and In Silico ADMETox Studies

CLD Ortiz, GC Completo, RC Nacario, RB Nellas - Scientific reports, 2019 - nature.com
A strategy in the discovery of anti-tuberculosis (anti-TB) drug involves targeting the enzymes
involved in the biosynthesis of Mycobacterium tuberculosis'(Mtb) cell wall. One of these …

ADMET profile and virtual screening of plant and microbial natural metabolites as SARS-CoV-2 S1 glycoprotein receptor binding domain and main protease inhibitors

S Padhi, M Masi, R Chourasia, Y Rajashekar… - European journal of …, 2021 - Elsevier
In an attempt to search for selective inhibitors against the SARS-CoV-2 which caused
devastating of lives and livelihoods across the globe, 415 natural metabolites isolated from …

Novel trends, challenges and new perspectives for enamel repair and regeneration to treat dental defects

F Mohabatpour, X Chen, S Papagerakis… - Biomaterials …, 2022 - pubs.rsc.org
Dental enamel is the hardest tissue in the human body, providing external protection for the
tooth against masticatory forces, temperature changes and chemical stimuli. Once enamel is …