In vivo imaging technologies have emerged as a powerful tool for both fundamental
research and clinical practice. In particular, luminescence imaging in the tissue-transparent …

For unique surface plasmon absorption and fluorescence characteristics, gold nanorods
have been developed and widely employed in the biomedical field. However, limitations still …

Unraveling the transport of drugs and nanocarriers in cerebrovascular networks is important
for pharmacokinetic and hemodynamic studies but is challenging due to the complexity of …

Leptomeningeal collaterals (LMCs) connect the main cerebral arteries and provide
alternative pathways for blood flow during ischaemic stroke. This is beneficial for reducing …

High-speed laser scanning microscopes are essential for monitoring fast biological
phenomena. However, existing strategies that achieve millisecond time resolution with two …

The pial vasculature is the sole source of blood supply to the neocortex. The brain is
contained within the skull, a vascularized bone marrow with a unique anatomical connection …

Significance The accurate large-scale mapping of cerebral microvascular blood flow velocity
is crucial for a better understanding of cerebral blood flow (CBF) regulation. Although optical …

Abstract Objective Dynamic Ultrasound Localization Microscopy (DULM) has first been
developed for non-invasive Pulsatility measurements in the rodent brain. DULM relies on the …

Precise matching of energy substrate delivery to local metabolic needs is essential for the
health and function of all tissues. Here, we outline a mechanistic framework for …

Large-scale imaging of brain activity with high spatio-temporal resolution is crucial for
advancing our understanding of brain function. The existing neuroimaging techniques are …