Tendon disorders are common and lead to significant disability, pain, healthcare cost, and
lost productivity. A wide range of injury mechanisms exist leading to tendinopathy or tendon …

Tendons and ligaments are extracellular matrix (ECM)-rich structures that interconnect
muscles and bones. Recent work has shown how tendon fibroblasts (tenocytes) interact with …

During embryogenesis, the musculoskeletal system develops while containing within itself a
force generator in the form of the musculature. This generator becomes functional relatively …

Formation of oriented myofibrils is a key event in musculoskeletal development. However,
the mechanisms that drive myocyte orientation and fusion to control muscle directionality in …

Mechanical forces between cells and extracellular matrix (ECM) influence cell shape and
function. Tendons are ECM-rich tissues connecting muscles with bones that bear extreme …

The molecular programme underlying tendon development has not been fully identified.
Interactions with components of the musculoskeletal system are important for limb tendon …

Tendon is a uniaxial connective tissue component of the musculoskeletal system. Tendon is
involved in force transmission between muscle and bone. Tendon injury is very common …

Tendons are extracellular matrix (ECM)-rich structures that mediate muscle attachments with
the skeleton, but surprisingly little is known about molecular mechanisms of attachment …

Although there have been several advances identifying novel mediators of tendon induction,
differentiation, and patterning, much of the basic landscape of tendon biology from …

Tendons and ligaments are fibrous connective tissues vital to the transmission of force and
stabilization of the musculoskeletal system. Arising in precise regions of the embryo …