The cytoskeleton—a complex interacting meshwork

T Hohmann, F Dehghani - Cells, 2019 - mdpi.com
The cytoskeleton of animal cells is one of the most complicated and functionally versatile
structures, involved in processes such as endocytosis, cell division, intra-cellular transport …

Microtubules in cell migration

C Garcin, A Straube - Essays in biochemistry, 2019 - portlandpress.com
Directed cell migration is critical for embryogenesis and organ development, wound healing
and the immune response. Microtubules are dynamic polymers that control directional …

[HTML][HTML] FUS inclusions disrupt RNA localization by sequestering kinesin-1 and inhibiting microtubule detyrosination

K Yasuda, SF Clatterbuck-Soper… - The Journal of cell …, 2017 - ncbi.nlm.nih.gov
Cytoplasmic inclusions of the RNA-binding protein fused in sarcoma (FUS) represent one
type of membraneless ribonucleoprotein compartment. Formation of FUS inclusions is …

HIV-1 capsid exploitation of the host microtubule cytoskeleton during early infection

MH Naghavi - Retrovirology, 2021 - Springer
Microtubules (MTs) form a filamentous array that provide both structural support and a
coordinated system for the movement and organization of macromolecular cargos within the …

Microtubules: Evolving roles and critical cellular interactions

CM Logan, AS Menko - Experimental Biology and Medicine, 2019 - journals.sagepub.com
Microtubules are cytoskeletal elements known as drivers of directed cell migration, vesicle
and organelle trafficking, and mitosis. In this review, we discuss new research in the lens …

An atlas of human kinase regulation

D Ochoa, M Jonikas, RT Lawrence… - Molecular systems …, 2016 - embopress.org
The coordinated regulation of protein kinases is a rapid mechanism that integrates diverse
cues and swiftly determines appropriate cellular responses. However, our understanding of …

Role of microtubules and microtubule-associated proteins in HIV-1 infection

A Dharan, EM Campbell - Journal of virology, 2018 - Am Soc Microbiol
Recent studies show that human immunodeficiency virus type 1 (HIV-1) can utilize
microtubules and their associated proteins to complete key postfusion steps during infection …

HIV Infection: Shaping the Complex, Dynamic, and Interconnected Network of the Cytoskeleton

R Cabrera-Rodríguez, S Pérez-Yanes… - International journal of …, 2023 - mdpi.com
HIV-1 has evolved a plethora of strategies to overcome the cytoskeletal barrier (ie, actin and
intermediate filaments (AFs and IFs) and microtubules (MTs)) to achieve the viral cycle. HIV …

Distinct functions of diaphanous-related formins regulate HIV-1 uncoating and transport

MK Delaney, V Malikov, Q Chai… - Proceedings of the …, 2017 - National Acad Sciences
Diaphanous (Dia)-related formins (DRFs) coordinate cytoskeletal remodeling by controlling
actin nucleation and microtubule (MT) stabilization to facilitate processes such as cell …

The multiple functions of kinesin-4 family motor protein KIF4 and its clinical potential

L Sheng, SL Hao, WX Yang, Y Sun - Gene, 2018 - Elsevier
Human KIF4 is a member of Kinesin-4 kinesin family. The highly conserved structure
contains an N-terminal motor region, coiled-coil region and C-terminal loading region. KIF4 …