[HTML][HTML] Carcinoma of the stomach: A review of epidemiology, pathogenesis, molecular genetics and chemoprevention

S Nagini - World journal of gastrointestinal oncology, 2012 - ncbi.nlm.nih.gov
Carcinoma of the stomach is still the second most common cause of cancer death
worldwide, although the incidence and mortality have fallen dramatically over the last 50 …

[HTML][HTML] Cellular and molecular aspects of gastric cancer

MG Smith, GL Hold, E Tahara… - World journal of …, 2006 - ncbi.nlm.nih.gov
Gastric cancer remains a global killer with a shifting burden from the developed to the
developing world. The cancer develops along a multistage process that is defined by distinct …

p53 alteration in gastric precancerous lesions.

YH Shiao, M Rugge, P Correa… - The American journal …, 1994 - ncbi.nlm.nih.gov
It has been postulated that chronic atrophic gastritis, intestinal metaplasia, and dysplasia are
precancerous stages of stomach tumorigenesis. We investigated the timing of p53 …

Molecular mechanism of stomach carcinogenesis

E Tahara - Journal of cancer research and clinical oncology, 1993 - Springer
Gene changes in multiple oncogenes, multiple growth factors and multiple tumor-suppressor
genes are observed in stomach cancer. Among them, those most commonly implicated in …

Cytogenetic and molecular aspects of gastric cancer: clinical implications

AD Panani - Cancer letters, 2008 - Elsevier
Gastric cancer is of major importance world-wide being the second most common cause of
cancer-related death in the world. According to Lauren's histological classification gastric …

Isoforms of the p53 family and gastric cancer: a menage a trois for an unfinished affair

A Blanchet, A Bourgmayer, JE Kurtz, G Mellitzer… - Cancers, 2021 - mdpi.com
Simple Summary The p53 family is a complex family of transcription factors with different
cellular functions that are involved in several physiological processes. A massive amount of …

HER2 expression and its clinicopathological features in resectable gastric cancer

Y Kataoka, H Okabe, A Yoshizawa, S Minamiguchi… - Gastric Cancer, 2013 - Springer
Background A recent randomized controlled trial (Trastuzumab for Gastric Cancer [ToGA]
study) established standard scoring criteria of human epidermal growth factor receptor 2 …

Genetic and epigenetic changes in stomach cancer

H Yokozaki, W Yasui, E Tahara - 2001 - Elsevier
Genetic and epigenetic alterations of multiple cancer-related genes and molecules are
implicated in the development and progression of human gastric carcinomas. Reactivation …

Intestinal metaplasia: a premalignant lesion involved in gastric carcinogenesis

RA Busuttil, A Boussioutas - Journal of gastroenterology and …, 2009 - Wiley Online Library
Despite a plateau in incidence, gastric cancer remains a significant problem globally. The
majority of gastric cancer is associated with histologically recognizable premalignant stages …

Cloning of a G‐protein‐coupled receptor that shows an activity to transform NIH3T3 cells and is expressed in gastric cancer cells

S Okumura, H Baba, T Kumada, K Nanmoku… - Cancer …, 2004 - Wiley Online Library
The present study was directed towards the identification of novel factors involved in the
transformation process leading to the formation of gastric cancer. A cDNA library from …