Plant-derived extracellular vesicles: a novel nanomedicine approach with advantages and challenges

M Nemati, B Singh, RA Mir, M Nemati, A Babaei… - Cell Communication and …, 2022 - Springer
Background Many eukaryote cells produce membrane-enclosed extracellular vesicles (EVs)
to establish cell-to-cell communication. Plant-derived EVs (P-EVs) contain proteins, RNAs …

Plant‐derived vesicle‐like nanoparticles as promising biotherapeutic tools: Present and future

J Feng, Q Xiu, Y Huang, Z Troyer, B Li… - Advanced …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are heterogeneous, phospholipid bilayer‐enclosed biological
particles that regulate cell communication by molecular cargo delivery and surface …

RNA-binding proteins contribute to small RNA loading in plant extracellular vesicles

B He, Q Cai, L Qiao, CY Huang, S Wang, W Miao, T Ha… - Nature plants, 2021 - nature.com
Plants use extracellular vesicles (EVs) to transport small RNAs (sRNAs) into their fungal
pathogens and silence fungal virulence-related genes through a phenomenon called 'cross …

Technology insight: Plant-derived vesicles—How far from the clinical biotherapeutics and therapeutic drug carriers?

M Cong, S Tan, S Li, L Gao, L Huang, HG Zhang… - Advanced drug delivery …, 2022 - Elsevier
Within the past decades, extracellular vesicles (EVs) have emerged as important mediators
of intercellular communication in both prokaryotes and higher eukaryotes to regulate a …

Message in a bubble: shuttling small RNAs and proteins between cells and interacting organisms using extracellular vesicles

Q Cai, B He, S Wang, S Fletcher, D Niu… - Annual review of …, 2021 - annualreviews.org
Communication between plant cells and interacting microorganisms requires the secretion
and uptake of functional molecules to and from the extracellular environment and is …

Novel plant-derived exosome-like nanovesicles from Catharanthus roseus: preparation, characterization, and immunostimulatory effect via TNF-α/NF-κB/PU.1 axis

X Ou, H Wang, H Tie, J Liao, Y Luo, W Huang… - Journal of …, 2023 - Springer
Background Plant-derived exosomes-like nanovesicles (PDENs) have been found to be
advantageous in disease treatment and drug delivery, but research on their biogenesis …

The emerging role of plant-derived exosomes-like nanoparticles in immune regulation and periodontitis treatment

Z Zhang, Y Yu, G Zhu, L Zeng, S Xu, H Cheng… - Frontiers in …, 2022 - frontiersin.org
Periodontitis is an infectious oral disease, which leads to the destruction of periodontal
tissues and tooth loss. Although the treatment of periodontitis has improved recently, the …

Plant extracellular vesicles

Y Cui, J Gao, Y He, L Jiang - Protoplasma, 2020 - Springer
Exocytosis is a key mechanism for delivering materials into the extracellular space for cell
function and communication. In plant cells, conventional protein secretion (CPS) is achieved …

Plant extracellular vesicles are incorporated by a fungal pathogen and inhibit its growth

M Regente, M Pinedo, H San Clemente… - Journal of …, 2017 - academic.oup.com
Extracellular vesicles (EV) are membrane particles released by cells into their environment
and are considered to be key players in intercellular communication. EV are produced by all …

Building a plant cell wall at a glance

ER Lampugnani, GA Khan, M Somssich… - Journal of Cell …, 2018 - journals.biologists.com
Plant cells are surrounded by a strong polysaccharide-rich cell wall that aids in determining
the overall form, growth and development of the plant body. Indeed, the unique shapes of …