Combined chemotherapeutic treatment is the method of choice for advanced and metastatic
gastric tumors. However, resistance to chemotherapeutic agents is one of the main …

Abstract Changes in potential regulatory elements are thought to be key drivers of
phenotypic divergence. However, identifying changes to regulatory elements that underlie …

Understanding transcription factor (TF) regulation of limbal epithelial stem/progenitor cells
(LEPCs) may aid in using non-ocular cells to regenerate the corneal surface. This study …

Cadmium (Cd) can induce ovarian injury by microRNAs (miRNAs), however, the molecular
mechanism of miRNAs after Cd exposure have not known. In this study, 56-day-old adult …

Metabolism and circadian rhythms are intimately linked, with circadian glucagon-like peptide-
1 (GLP-1) secretion by the intestinal L-cell entraining rhythmic insulin release. GLP-1 …

Intestinal cell dysfunctions involved in obesity and associated diabetes could be correlated
with impaired intestinal cell development. To date, the molecular mechanisms underlying …

Background Intestinal barrier impairment plays an essential role in the pathogenesis of
Crohn's disease (CD), and claudins (CLDNs) dysfunction contributes to intestinal mucosa …

Increasing evidences have suggested that deregulated miRNAs may involve in drug
chemoresistance in a lot of human cancers. However, the role of miR-613 in drug …

To investigate the role of DNA methylation in modulating chronic neuropathic pain (NPP),
identify possible target genes of DNA methylation involved in this process, and preliminarily …

Selective intrauterine growth restriction (sIUGR) is a severe complication in monochorionic
(MC) twin pregnancies, and it carries increased risks of poor prognosis. Current data …