Pathogenesis of Behçet's syndrome: genetic, environmental and immunological factors

I Mattioli, A Bettiol, G Saruhan-Direskeneli… - Frontiers in …, 2021 - frontiersin.org
Behçet's syndrome (BS) is a rare systemic vasculitis, characterized by a wide range of
different clinical involvements and unpredictable phases of recurrence and remission. BS …

A comprehensive review on miR-146a molecular mechanisms in a wide spectrum of immune and non-immune inflammatory diseases

SS Mortazavi-Jahromi, M Aslani, A Mirshafiey - Immunology Letters, 2020 - Elsevier
MicroRNAs (miRNAs) are single-strand endogenous and non-coding RNA molecules with a
length of about 22 nucleotides, which regulate genes expression, through modulating the …

MicroRNAs and autoimmune-mediated eye diseases

Y Wei, N Li, L Zhao, C Yang, B Ma, X Li… - Frontiers in Cell and …, 2020 - frontiersin.org
MicroRNAs (miRNAs) are evolutionarily conserved short non-coding RNAs that act at post-
transcriptional regulation of gene expression by destroying target messenger RNA or …

MicroRNA367 negatively regulates the inflammatory response of microglia by targeting IRAK4 in intracerebral hemorrhage

B Yuan, H Shen, L Lin, T Su, L Zhong… - Journal of …, 2015 - Springer
Background Intracerebral hemorrhage (ICH) induces microglial activation and the release of
inflammatory cytokines, leading to inflammation in the brain. IRAK4, an essential component …

[PDF][PDF] Behçet's syndrome: a critical digest of the 2014-2015 literature

G Hatemi, E Seyahi, I Fresko, R Talarico… - Clin Exp …, 2015 - clinexprheumatol.org
Several studies were published last year which focused on the epidemiology,
immunopathogenesis, genetics, clinical manifestations and management of Behçet's …

Focus on neuro-Behçet's disease: a review

P Caruso, R Moretti - Neurology India, 2018 - journals.lww.com
Behçet's disease (BD) is a multisystemic vasculitis disorder of almost unknown etiology,
which involves small and large vessels and affects both veins and arteries. BD is …

Precursor miR-499a variant but not miR-196a2 is associated with rheumatoid arthritis susceptibility in an Egyptian population

EA Toraih, NM Ismail, AA Toraih, MH Hussein… - Molecular diagnosis & …, 2016 - Springer
Introduction Rheumatoid arthritis (RA) has a complex component induced by several genes
that interact together with environmental and hormonal factors. We aimed to investigate the …

Association between the three functional miR-146a single-nucleotide polymorphisms, rs2910164, rs57095329, and rs2431697, and autoimmune disease …

R Park, WJ Lee, JD Ji - Autoimmunity, 2016 - Taylor & Francis
Studies suggest associations between the miR-146a single nucleotide polymorphisms
(SNPs) and susceptibility to autoimmune diseases. However, the results are inconsistent …

Genetics of Behçet's disease

LT Morton, D Situnayake… - Current opinion in …, 2016 - journals.lww.com
Genetic and epigenetic changes affecting cells and molecules involved in Behçet's disease
offer new pathways for research, including cytoskeletal protein function, that will provide new …

Variants of MIRNA146A rs2910164 and MIRNA499 rs3746444 are associated with the development of cutaneous leishmaniasis caused by Leishmania guyanensis …

TGR de Mesquita, JES Junior… - PLoS neglected …, 2021 - journals.plos.org
Leishmania are intracellular protozoan parasites that cause a wide spectrum of clinical
manifestations in genetically susceptible individuals with an insufficient or balanced Th1 …