The mitochondrial calcium uniporter is an evolutionarily conserved calcium channel, and its
biophysical properties and relevance to cell death, bioenergetics and signalling have been …

Evolving 40 times independently, eyes are striking examples of convergent evolution in that
11-cis retinaldehyde is always used for photon capture, yet the mechanism for its …

The grail of protein science is the connection between structure and function. For myoglobin
(Mb) this goal is close. Described as only a passive dioxygen storage protein in texts, we …

Myoglobin (Mb) is perhaps the most studied protein, experimentally and theoretically.
Despite the wealth of known details regarding the gas migration processes inside Mb, there …

The relationship between skeletal muscle intracellular Po 2 (iPo 2) and progressive
muscular work has important implications for the understanding of O2 transport and …

Hemoproteins are widely distributed among unicellular eukaryotes, plants, and animals. In
addition to myoglobin and hemoglobin, a third hemoprotein, neuroglobin, has recently been …

Myoglobin is an oxygen storage molecule that is selectively expressed in cardiac and slow-
twitch skeletal muscles that have a high oxygen demand. Numerous studies have implicated …

Metastases from prostatic adenocarcinoma (prostate cancer) are characterized by their
predilection for bone and typical osteoblastic features. An in vitro model of bone metastases …

The effect of pH (6.0, 6.5, and 7.0) on lipid oxidation in washed Asian seabass (Lates
calcarifer) mince mediated by oxymyoglobin from the dark muscle of little Eastern tuna …

A canonical view of the primary physiological function of myoglobin (Mb) is that it is an
oxygen (O2) storage protein supporting mitochondrial oxidative phosphorylation, especially …