Role of autophagy in aging: The good, the bad, and the ugly

S Tabibzadeh - Aging Cell, 2023 - Wiley Online Library
Autophagy (self‐eating) is a conserved catabolic homeostatic process required for cellular
metabolic demands by removal of the damaged molecules and organelles and for …

Fueling the cell division cycle

M Salazar-Roa, M Malumbres - Trends in cell biology, 2017 - cell.com
Cell division is a complex process with high energy demands. However, how cells regulate
the generation of energy required for DNA synthesis and chromosome segregation is not …

[HTML][HTML] Autophagy and oxidative stress in cardiovascular diseases

Y Mei, MD Thompson, RA Cohen, XY Tong - Biochimica et Biophysica Acta …, 2015 - Elsevier
Autophagy is a highly conserved degradation process by which intracellular components,
including soluble macromolecules (eg nucleic acids, proteins, carbohydrates, and lipids) …

Autophagy and the cell cycle: a complex landscape

SG Mathiassen, D De Zio, F Cecconi - Frontiers in oncology, 2017 - frontiersin.org
Autophagy is a self-degradation pathway, in which cytoplasmic material is sequestered in
double-membrane vesicles and delivered to the lysosome for degradation. Under basal …

Autophagy and aging

N Martinez-Lopez, D Athonvarangkul… - Longevity Genes: A …, 2015 - Springer
Autophagy is a critical quality control pathway that is conserved across diverse systems
ranging from simple unicellular organisms like yeast to more complex systems, for instance …

Mechanisms of autophagy in metabolic stress response

AS Gross, M Graef - Journal of molecular biology, 2020 - Elsevier
Autophagy is a highly conserved catabolic pathway critical for stress responses and the
maintenance of cellular homeostasis. Defective autophagy contributes to the etiology of an …

Basic science and pathogenesis of ageing with HIV: potential mechanisms and biomarkers

C Lagathu, A Cossarizza, V Béréziat, M Nasi, J Capeau… - Aids, 2017 - journals.lww.com
The increased prevalence of age-related comorbidities and mortality is worrisome in ageing
HIV-infected patients. Here, we aim to analyse the different ageing mechanisms with regard …

The coordinated action of the MVB pathway and autophagy ensures cell survival during starvation

M Müller, O Schmidt, M Angelova, K Faserl, S Weys… - Elife, 2015 - elifesciences.org
The degradation and recycling of cellular components is essential for cell growth and
survival. Here we show how selective and non-selective lysosomal protein degradation …

Improvement of cis,cis-Muconic Acid Production in Saccharomyces cerevisiae through Biosensor-Aided Genome Engineering

G Wang, S Øzmerih, R Guerreiro… - ACS synthetic …, 2020 - ACS Publications
Muconic acid is a potential platform chemical for the production of nylon, polyurethanes, and
terephthalic acid. It is also an attractive functional copolymer in plastics due to its two double …

Molecular pathways: autophagy in cancer—a matter of timing and context

M Cicchini, V Karantza, B Xia - Clinical cancer research, 2015 - AACR
Autophagy is an intracellular self-digestion mechanism, by which cellular components are
sorted into double-membrane autophagosomes and delivered to lysosomes for degradation …