Cardiovascular disease is the leading cause of death worldwide. Although investment in
drug discovery and development has been sky-rocketing, the number of approved drugs has …

Cellular therapy for cardiovascular disease heralds an exciting frontier of research.
Mesenchymal stromal cells (MSCs) are present in adult tissues, including bone marrow and …

Recent studies have suggested that bone marrow cells might possess a much broader
differentiation potential than previously appreciated. In most cases, the reported efficiency of …

There is an urgent clinical need to develop new therapeutic approaches for treating
cardiovascular disease, but the biology of cardiovascular regeneration is complex. Model …

Doxorubicin-induced cardiotoxicity in childhood cancer survivors is a growing problem. The
population of patients at risk for cardiovascular disease is steadily increasing, as five-year …

The ischemia-induced death of cardiomyocytes results in scar formation and reduced
contractility of the ventricle. Several preclinical and clinical studies have supported the …

Objectives: The present study was designed as a face-to-face functional comparison of
human skeletal myoblasts (SMs) and CD133+ bone marrow-derived hematopoietic …

Limited data are available on the effects of stem cells in non-ischemic dilated
cardiomyopathy (DCM). Since the diffuse nature of the disease calls for a broad distribution …

After myocardial infarction, injured cardiomyocytes are replaced by fibrotic tissue promoting
the development of heart failure. Cell transplantation has emerged as a potential therapy …

The conductive polymer polypyrrole was blended with alginate to investigate its potential in
tissue engineering applications. This study showed that increasing the polypyrrole content …