Pathogenic mechanisms underlying idiopathic pulmonary fibrosis
The pathogenesis of idiopathic pulmonary fibrosis (IPF) involves a complex interplay of cell
types and signaling pathways. Recurrent alveolar epithelial cell (AEC) injury may occur in …
types and signaling pathways. Recurrent alveolar epithelial cell (AEC) injury may occur in …
Global incidence and prevalence of idiopathic pulmonary fibrosis
Background Idiopathic pulmonary fibrosis (IPF) is a progressive debilitating lung disease
with considerable morbidity. Heterogeneity in epidemiologic studies means the full impact of …
with considerable morbidity. Heterogeneity in epidemiologic studies means the full impact of …
A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models
Idiopathic pulmonary fibrosis (IPF) is an aggressive interstitial lung disease with a high
mortality rate. Putative drug targets in IPF have failed to translate into effective therapies at …
mortality rate. Putative drug targets in IPF have failed to translate into effective therapies at …
Idiopathic pulmonary fibrosis: state of the art for 2023
AJ Podolanczuk, CC Thomson… - European …, 2023 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease characterised by
worsening respiratory symptoms and physiological impairment. Increasing awareness of the …
worsening respiratory symptoms and physiological impairment. Increasing awareness of the …
Emerging cellular and molecular determinants of idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF), the most common form of idiopathic interstitial
pneumonia, is a progressive, irreversible, and typically lethal disease characterized by an …
pneumonia, is a progressive, irreversible, and typically lethal disease characterized by an …
Diagnosis of idiopathic pulmonary fibrosis. An official ATS/ERS/JRS/ALAT clinical practice guideline
G Raghu, M Remy-Jardin, JL Myers… - American journal of …, 2018 - atsjournals.org
Background: This document provides clinical recommendations for the diagnosis of
idiopathic pulmonary fibrosis (IPF). It represents a collaborative effort between the American …
idiopathic pulmonary fibrosis (IPF). It represents a collaborative effort between the American …
Association between preserved ratio impaired spirometry and clinical outcomes in US adults
Importance Chronic lung diseases are a leading cause of morbidity and mortality. Unlike
chronic obstructive pulmonary disease, clinical outcomes associated with proportional …
chronic obstructive pulmonary disease, clinical outcomes associated with proportional …
[HTML][HTML] The impact of the lung environment on macrophage development, activation and function: diversity in the face of adversity
CC Bain, AS MacDonald - Mucosal immunology, 2022 - Elsevier
The last decade has been somewhat of a renaissance period for the field of macrophage
biology. This renewed interest, combined with the advent of new technologies and …
biology. This renewed interest, combined with the advent of new technologies and …
Idiopathic pulmonary fibrosis
L Richeldi, HR Collard, MG Jones - The Lancet, 2017 - thelancet.com
Idiopathic pulmonary fibrosis is a prototype of chronic, progressive, and fibrotic lung disease.
Healthy tissue is replaced by altered extracellular matrix and alveolar architecture is …
Healthy tissue is replaced by altered extracellular matrix and alveolar architecture is …
Developmental pathways in the pathogenesis of lung fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive and terminal lung disease with no known
cure. IPF is a disease of aging, with median age of diagnosis over 65 years. Median survival …
cure. IPF is a disease of aging, with median age of diagnosis over 65 years. Median survival …