This review describes the progress that has been achieved since adaptive optics (AO) was
incorporated into the ophthalmoscope a quarter of a century ago, transforming our ability to …

Twenty-five years ago, adaptive optics (AO) was combined with fundus photography,
thereby initiating a new era in the field of ophthalmic imaging. Since that time, clinical …

Aging is the greatest risk factor for chronic human diseases, including many eye diseases.
Geroscience aims to understand the effects of the aging process on these diseases …

This is a comprehensive review of the principles and applications of adaptive optics (AO) in
ophthalmology. It has been combined with flood illumination ophthalmoscopy, scanning …

Purpose: The human retinal pigment epithelium (RPE) accumulates granules significant for
autofluorescence imaging. Knowledge of intracellular accumulation and distribution is …

Diseases that result in retinal pigment epithelium (RPE) degeneration, such as age-related
macular degeneration (AMD), are among the leading causes of blindness worldwide …

Purpose: To quantify organelles impacting imaging in the cell body and intact apical
processes of human retinal pigment epithelium (RPE), including melanosomes, lipofuscin …

We describe the design and performance of a multimodal and multifunctional adaptive
optics (AO) system that combines scanning laser ophthalmoscopy (SLO) and optical …

The retinal pigment epithelium (RPE) is a unique epithelium, with major roles which are
essential in the visual cycle and homeostasis of the outer retina. The RPE is a monolayer of …

In vivo imaging of human retinal pigment epithelial (RPE) cells has been demonstrated
through multiple adaptive optics (AO)-based modalities. However, whether consistent and …