Melatonin, the neurohormone of the pineal gland, is also produced by various other tissues
and cells. It acts via G protein-coupled receptors expressed in various areas of the central …

This review aims at describing the beneficial properties of melatonin related to its antioxidant
effects. Oxidative stress, ie, an imbalance between the production of reactive oxygen …

Background: Night shift work, exposure to light at night (ALAN) and circadian disruption may
increase the risk of hormone-dependent cancers. Objectives: We evaluated the association …

Alzheimer's disease (AD) is a chronic, progressive and prevalent neurodegenerative
disease characterized by the loss of higher cognitive functions and an associated loss of …

OBJECTIVE: To summarize the role of melatonin in the physiology and pathophysiology of
the ovary. DESIGN: Review of literature. SETTING: University Health Science Center …

Melatonin, the major secretory product of the pineal gland, not only regulates circadian
rhythms, mood, and sleep but also has actions in neoplastic processes which are being …

Oxidative stress plays a key role in the pathogenesis of aging and many metabolic diseases;
therefore, an effective antioxidant therapy would be of great importance in these …

Diurnal rhythms influence cardiovascular physiology, ie heart rate and blood pressure, and
they appear to also modulate the incidence of serious adverse cardiac events. Diurnal …

Photoperiodism is the ability of plants and animals to measure environmental day length to
ascertain time of year. Central to the evolution of photoperiodism in animals is the adaptive …

Reactivation of silenced tumor suppressor genes by 5-azacytidine (Vidaza) and its congener
5-aza-2′-deoxycytidine (decitabine) has provided an alternate approach to cancer therapy …