Long non-coding RNAs and their biological roles in plants

X Liu, L Hao, D Li, L Zhu, S Hu - Genomics, proteomics and …, 2015 - academic.oup.com
With the development of genomics and bioinformatics, especially the extensive applications
of high-throughput sequencing technology, more transcriptional units with little or no protein …

Methods for distinguishing between protein-coding and long noncoding RNAs and the elusive biological purpose of translation of long noncoding RNAs

G Housman, I Ulitsky - Biochimica et Biophysica Acta (BBA)-Gene …, 2016 - Elsevier
Long noncoding RNAs (lncRNAs) are a diverse class of RNAs with increasingly appreciated
functions in vertebrates, yet much of their biology remains poorly understood. In particular, it …

FEELnc: a tool for long non-coding RNA annotation and its application to the dog transcriptome

V Wucher, F Legeai, B Hédan, G Rizk… - Nucleic acids …, 2017 - academic.oup.com
Whole transcriptome sequencing (RNA-seq) has become a standard for cataloguing and
monitoring RNA populations. One of the main bottlenecks, however, is to correctly identify …

Evaluation of deep learning in non-coding RNA classification

N Amin, A McGrath, YPP Chen - Nature Machine Intelligence, 2019 - nature.com
Non-coding (nc) RNA plays a vital role in biological processes and has been associated
with diseases such as cancer. Classification of ncRNAs is necessary for understanding the …

CPPred: coding potential prediction based on the global description of RNA sequence

X Tong, S Liu - Nucleic acids research, 2019 - academic.oup.com
The rapid and accurate approach to distinguish between coding RNAs and ncRNAs has
been playing a critical role in analyzing thousands of novel transcripts, which have been …

LncRNAnet: long non-coding RNA identification using deep learning

J Baek, B Lee, S Kwon, S Yoon - Bioinformatics, 2018 - academic.oup.com
Abstract Motivation Long non-coding RNAs (lncRNAs) are important regulatory elements in
biological processes. LncRNAs share similar sequence characteristics with messenger …

Inferring potential CircRNA–disease associations via deep autoencoder-based classification

K Deepthi, AS Jereesh - Molecular Diagnosis & Therapy, 2021 - Springer
Abstract Aim Circular RNAs (circRNA) are endogenous non-coding RNA molecules with a
stable circular conformation. Growing evidence from recent experiments reveals that …

GraphCDA: a hybrid graph representation learning framework based on GCN and GAT for predicting disease-associated circRNAs

Q Dai, Z Liu, Z Wang, X Duan… - Briefings in …, 2022 - academic.oup.com
Motivation: CircularRNA (circRNA) is a class of noncoding RNA with high conservation and
stability, which is considered as an important disease biomarker and drug target …

nRC: non-coding RNA Classifier based on structural features

A Fiannaca, M La Rosa, L La Paglia, R Rizzo, A Urso - BioData mining, 2017 - Springer
Abstract Motivation Non-coding RNA (ncRNA) are small non-coding sequences involved in
gene expression regulation of many biological processes and diseases. The recent …

DeepLNC, a long non-coding RNA prediction tool using deep neural network

R Tripathi, S Patel, V Kumari, P Chakraborty… - … Modeling Analysis in …, 2016 - Springer
The significant role of long non-coding RNAs (lncRNAs) in various cellular functions, such
as gene imprinting, immune response, embryonic pluripotency, tumorogenesis, and genetic …