Association of KIR genes and MHC class I ligands with atopic dermatitis
Atopic dermatitis (AD) is a chronic illness that is associated with immune dysregulation. NK
cell function has previously been associated with AD. NK cells directly interact with …
cell function has previously been associated with AD. NK cells directly interact with …
[HTML][HTML] Systematic identification of genotype-dependent enhancer variants in eosinophilic esophagitis
Eosinophilic esophagitis (EoE) is a rare atopic disorder associated with esophageal
dysfunction, including difficulty swallowing, food impaction, and inflammation, that develops …
dysfunction, including difficulty swallowing, food impaction, and inflammation, that develops …
Association between atopic dermatitis, autoimmune illnesses, Epstein-Barr virus, and cytomegalovirus
ZCC Fuxench, N Mitra, OJ Hoffstad, EJ Phillips… - Archives of …, 2023 - Springer
Atopic dermatitis (AD) is a Th2-driven inflammatory skin disease that has been associated
with other autoimmune illnesses (AI) and has a well-known predisposition to infection with …
with other autoimmune illnesses (AI) and has a well-known predisposition to infection with …
Atopy as immune dysregulation: offender genes and targets
Allergic diseases are a heterogeneous group of disorders resulting from exaggerated type 2
inflammation. Although typically viewed as polygenic multifactorial disorders caused by the …
inflammation. Although typically viewed as polygenic multifactorial disorders caused by the …
Genomic characterization of HLA class I and class II genes in ethnically diverse sub‐Saharan African populations: A report on novel HLA alleles
I Pagkrati, JL Duke, E Mbunwe, TL Mosbruger… - Hla, 2023 - Wiley Online Library
HLA allelic variation has been well studied and documented in many parts of the world.
However, African populations have been relatively under‐represented in studies of HLA …
However, African populations have been relatively under‐represented in studies of HLA …
[HTML][HTML] Association of KIR2DL5, KIR2DS5, and KIR2DS1 allelic variation and atopic dermatitis
Natural killer cells (NK) have been associated with the pathophysiology of atopic dermatitis
(AD). NK function is regulated by killer cell Ig-like receptor family (KIR) receptors that interact …
(AD). NK function is regulated by killer cell Ig-like receptor family (KIR) receptors that interact …
[HTML][HTML] Limited Clinical Impact of Genetic Associations between Celiac Disease and Type 2 Inflammatory Diseases: Insights from Mendelian Randomization
Background: Celiac disease, a gluten-triggered autoimmune disorder, is known for its
systemic inflammatory effects. Its genetic associations with type 2 inflammatory diseases like …
systemic inflammatory effects. Its genetic associations with type 2 inflammatory diseases like …
[HTML][HTML] A combination of HLA-DP α and β chain polymorphisms paired with a SNP in the DPB1 3'UTR region, denoting expression levels, are associated with atopic …
Introduction: Components of the immune response have previously been associated with
the pathophysiology of atopic dermatitis (AD), specifically the Human Leukocyte Antigen …
the pathophysiology of atopic dermatitis (AD), specifically the Human Leukocyte Antigen …
[HTML][HTML] KIR allelic variation and the remission of atopic dermatitis over time
Atopic dermatitis (AD) is a common chronic skin disease. Although generally thought to be a
disease of T-cell dysregulation, recent studies have suggested that immune dysregulation of …
disease of T-cell dysregulation, recent studies have suggested that immune dysregulation of …
HLA DRB5∗ 01: 01 is associated with pruritus in individuals with Fitzpatrick skin type IV-VI
A Kambala, A Rajeh, MZ Joel, E Ma, H Cornman… - Journal of the American …, 2024 - Elsevier
Journal of Investigative Dermatology 141, 754-760. e751, 87 doi: https://doi. org/10.1016/j.
jid. 2020.08. 020 (2021). 88 2 Sutaria, N. et al. Itch in skin of colour: a multicentre cross …
jid. 2020.08. 020 (2021). 88 2 Sutaria, N. et al. Itch in skin of colour: a multicentre cross …