▪ Abstract The transforming growth factor β (TGF-β) family of proteins are a set of pleiotropic
secreted signaling molecules with unique and potent immunoregulatory properties. TGF-β1 …

Periapical inflammatory responses occur as a consequence of bacterial infection of the
dental pulp, as a result of caries, trauma, or iatrogenic insult. Periapical inflammation …

An elusive goal in transplanting organs across histocompatibility barriers has been the
induction of specific tolerance to avoid graft rejection. A considerable body of evidence …

We have examined the effect of dexamethasone (DM) and cortisol on the production of
interleukin (IL) 6 from the murine macrophage cell line RAW 264.9, human monocytes …

Approximately 2 wk after birth, mice having a TGF-beta 1 null mutation (TGF-beta 1 (-/-))
exhibit a progressive wasting syndrome and death. Associated with this phenotype is a …

We investigated the profiles of cytokine mRNA expression in muscle in 15 cases of
inflammatory myopathy (IM)(5 each of polymyositis, inclusion body myositis, and …

This study evaluated the clinical efficacy of 2% chlorhexidine (CHX) gel on intracanal
bacteria reduction during root canal instrumentation. The additional antibacterial effect of an …

Various specific and non-specific environmental factors have been associated with the
induction and/or exacerbation of disease activity in patients with Crohn's disease and …

Transforming growth factor-beta (TGF-beta) inhibits B cell Ig secretion and reduces B cell
membrane Ig expression. The addition of TGF-beta to human B lymphocyte cultures …

Abstract Interleukin 6 (IL‐6) is a multifunctional cytokine regulating immune response, acute
phase reaction and hematopoiesis. IL‐6 plays a critical role in B cell differentiation to plasma …