Brain is a vital organ of the human body which performs very important functions such as
analysis, processing, coordination, and execution of electrical signals. For this purpose, it …

Myelin is critical for the proper function of the nervous system and one of the most complex
cell–cell interactions of the body. Myelination allows for the rapid conduction of action …

The integrity of central and peripheral nervous system myelin is affected in numerous lipid
metabolism disorders. This vulnerability was so far mostly attributed to the extraordinarily …

This textbook describes the basic principles of induced organ regeneration in skin and
peripheral nerves and extends the original successful paradigm to other organs. A set of …

Unlike its central counterpart, the peripheral nervous system is well known for its
comparatively good potential for regeneration following nerve fiber injury. This ability is …

In the past 20 years, PCSK9 has been shown to play a pivotal role in LDL cholesterol
metabolism and cardiovascular health by inducing the lysosomal degradation of the LDL …

Myelin consists of tightly compacted membranes that form an insulating sheath around
axons. The function of myelin for rapid saltatory nerve conduction is dependent on its unique …

We review the available evidence for regeneration of adult organs of very diverse nature
and examine the applicability of simple rules that can be used to summarize these …

Myelination of peripheral nerves by Schwann cells requires a large amount of lipid and
cholesterol biosynthesis. To understand the transcriptional coordination of the myelination …

Myelin consists of several layers of tightly compacted membranes wrapped around axons in
the nervous system. The main function of myelin is to provide electrical insulation around the …