Candida albicans morphogenesis and host defence: discriminating invasion from colonization
Candida albicans is a common fungal pathogen of humans that colonizes the skin and
mucosal surfaces of most healthy individuals. Until recently, little was known about the …
mucosal surfaces of most healthy individuals. Until recently, little was known about the …
Regulatory circuitry governing fungal development, drug resistance, and disease
Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …
frequency of fungal infections in immunocompromised populations and the limited …
Metabolism impacts upon Candida immunogenicity and pathogenicity at multiple levels
Metabolism is integral to the pathogenicity of Candida albicans, a major fungal pathogen of
humans. As well as providing the platform for nutrient assimilation and growth in diverse …
humans. As well as providing the platform for nutrient assimilation and growth in diverse …
Environmental Sensing and Signal Transduction Pathways Regulating Morphopathogenic Determinants of Candida albicans
Candida albicans is an opportunistic fungal pathogen that is found in the normal
gastrointestinal flora of most healthy humans. However, under certain environmental …
gastrointestinal flora of most healthy humans. However, under certain environmental …
Bacterial peptidoglycan triggers Candida albicans hyphal growth by directly activating the adenylyl cyclase Cyr1p
Human serum potently induces hyphal development of the polymorphic fungal pathogen
Candida albicans, a phenotype that contributes critically to infections. The fungal adenylyl …
Candida albicans, a phenotype that contributes critically to infections. The fungal adenylyl …
The metabolic basis of Candida albicans morphogenesis and quorum sensing
TL Han, RD Cannon, SG Villas-Bôas - Fungal Genetics and Biology, 2011 - Elsevier
Candida albicans is a polymorphic fungus that has the ability to rapidly switch between
yeast and filamentous forms. The morphological transition appears to be a critical virulence …
yeast and filamentous forms. The morphological transition appears to be a critical virulence …
Sugar Sensing and Signaling in Candida albicans and Candida glabrata
M Van Ende, S Wijnants, P Van Dijck - Frontiers in microbiology, 2019 - frontiersin.org
Candida species, such as Candida albicans and Candida glabrata, cause infections at
different host sites because they adapt their metabolism depending on the available …
different host sites because they adapt their metabolism depending on the available …
Adapting to survive: How Candida overcomes host-imposed constraints during human colonization
Successful human colonizers such as Candida pathogens have evolved distinct strategies
to survive and proliferate within the human host. These include sophisticated mechanisms to …
to survive and proliferate within the human host. These include sophisticated mechanisms to …
The G Protein-coupled Receptor Gpr1 and the Gα Protein Gpa2 Act through the cAMP-Protein Kinase A Pathway to Induce Morphogenesis in Candida albicans
MM Maidan, L De Rop, J Serneels, S Exler… - Molecular biology of …, 2005 - Am Soc Cell Biol
We investigated the role in cell morphogenesis and pathogenicity of the Candida albicans
GPR1 gene, encoding the G protein-coupled receptor Gpr1. Deletion of C. albicans GPR1 …
GPR1 gene, encoding the G protein-coupled receptor Gpr1. Deletion of C. albicans GPR1 …
Glucose Promotes Stress Resistance in the Fungal Pathogen Candida albicans
A Rodaki, IM Bohovych, B Enjalbert… - Molecular biology of …, 2009 - Am Soc Cell Biol
Metabolic adaptation, and in particular the modulation of carbon assimilatory pathways
during disease progression, is thought to contribute to the pathogenicity of Candida …
during disease progression, is thought to contribute to the pathogenicity of Candida …