Analytical reviews in clinical biochemistry: the estimation of urea

AJ Taylor, P Vadgama - Annals of clinical biochemistry, 1992 - journals.sagepub.com
Ammonia is a product of amino acid metabolism and the major source of circulating
ammonia is the gastrointestinal tract. 2 It is neurotoxic, possibly due to its effect on the …

A conventional and chemometric analytical approach to solving urea determination with accuracy and precision

MCG Pellá, AR Simão, P Valderrama, AF Rubira - Analytical Methods, 2023 - pubs.rsc.org
Urea is an essential molecule usually detected using spectroscopy, particularly ultraviolet
and visible spectroscopy (UV-vis). However, its detection represents a not always fully …

Selective ion monitoring in clinical chemistry

I Björkhem, AM Lawson - CRC Critical Reviews in Clinical …, 1979 - Taylor & Francis
The history of clinical and biological sciences is to a great extent that of the development of
different methodologies. Sooner or later, most biological problems lead to experimental …

Measurement of urea in human serum by isotope dilution mass spectrometry: a reference procedure

A Kessler, L Siekmann - Clinical Chemistry, 1999 - academic.oup.com
Background: A reference measurement procedure is needed to demonstrate the traceability
of results of urea measurements in human serum. We developed a measurement procedure …

Mass fragmentography of creatinine proposed as a reference method.

I Bjorkhem, R Blomstrand, G Ohman - 1977 - cabidigitallibrary.org
Creatinine is isolated from lyophilized serum or urine with added [15N2] creatinine by high-
performance liquid chromatography. It is converted to the di-trifluoroacetate of the (2 …

Perfomance study of urease-PMMA-based aqueous urea sensor

A Bose, K Biswas - IEEE Sensors Journal, 2017 - ieeexplore.ieee.org
This paper presents the development of a simple, low cost, the new type of urea sensor, and
suitable for water quality monitoring. Here, urease is immobilized on the electrodes using …

Determination of serum urea by isotope dilution mass spectrometry as a candidate definitive method

MJ Welch, A Cohen, HS Hertz, FC Ruegg… - Analytical …, 1984 - ACS Publications
An Isotope dilution mass spectrometrlc (ID/MS) method for serum urea Is described. The
method utilizes urea-180 as the labeled Internal standard and Involves Isolation of urea from …

Gas chromatography/mass spectrometric determination of [15N] urea in plasma and application to urea metabolism study

KY Tserng, SC Kalhan - Analytical Chemistry, 1982 - ACS Publications
The study of urea metabolism In humans necessitates sen-sitive methods, so that very low
Isotopic enrichments of plasma or urinary urea can be measured. A stable derivative of urea …

Determining urea levels in exhaled breath condensate with minimal preparation steps and classic LC–MS

M Pitiranggon, MS Perzanowski… - Journal of …, 2014 - academic.oup.com
Exhaled breath condensate (EBC) provides a relatively easy, non-invasive method for
measuring biomarkers of inflammation and oxidative stress in the airways. However, the …

Accuracy of some routine method used in clinical chemistry as judged by isotope dilution-mass spectrometry.

I Björkhem, A Bergman, O Falk, A Kallner… - Clinical …, 1981 - academic.oup.com
Serum from patients was pooled, filtered, dispensed, and frozen. This pooled specimen was
used for accuracy control in 64 participating laboratories in Sweden. Mean values (" state-of …