[HTML][HTML] Health benefits and side effects of short-chain fatty acids

RG Xiong, DD Zhou, SX Wu, SY Huang, A Saimaiti… - Foods, 2022 - mdpi.com
The gut microbiota and their metabolites could play an important role in health and diseases
of human beings. Short-chain fatty acids (SCFAs) are mainly produced by gut microbiome …

[HTML][HTML] Roseburia intestinalis: A Beneficial Gut Organism From the Discoveries in Genus and Species

K Nie, K Ma, W Luo, Z Shen, Z Yang, M Xiao… - Frontiers in cellular …, 2021 - frontiersin.org
Roseburia intestinalis is an anaerobic, Gram-positive, slightly curved rod-shaped flagellated
bacterium that produces butyrate in the colon. R. intestinalis has been shown to prevent …

[HTML][HTML] The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer

H Wang, X Rong, G Zhao, Y Zhou, Y Xiao, D Ma, X Jin… - Cell metabolism, 2022 - cell.com
Immunotherapy has achieved limited success in patients with triple-negative breast cancer
(TNBC), an aggressive disease with a poor prognosis. Commensal microbiota have been …

The role of short-chain fatty acids in intestinal barrier function, inflammation, oxidative stress, and colonic carcinogenesis

P Liu, Y Wang, G Yang, Q Zhang, L Meng, Y Xin… - Pharmacological …, 2021 - Elsevier
Short-chain fatty acids (SCFAs), mainly including acetate, propionate, and butyrate, are
metabolites produced during the bacterial fermentation of dietary fiber in the intestinal tract …

[HTML][HTML] Tomatoes: An extensive review of the associated health impacts of tomatoes and factors that can affect their cultivation

EJ Collins, C Bowyer, A Tsouza, M Chopra - Biology, 2022 - mdpi.com
Simple Summary The research outlined in this review paper discusses potential health
benefits associated with a diet enriched with tomatoes and tomato products. This includes …

[HTML][HTML] Intestinal microbiota-derived short chain fatty acids in host health and disease

J Cong, P Zhou, R Zhang - Nutrients, 2022 - mdpi.com
Intestinal microbiota has its role as an important component of human physiology. It
produces metabolites that module key functions to establish a symbiotic crosstalk with their …

Metabolic networks in mutant KRAS-driven tumours: tissue specificities and the microenvironment

SA Kerk, T Papagiannakopoulos, YM Shah… - Nature Reviews …, 2021 - nature.com
Oncogenic mutations in KRAS drive common metabolic programmes that facilitate tumour
survival, growth and immune evasion in colorectal carcinoma, non-small-cell lung cancer …

Fermentation and germination improve nutritional value of cereals and legumes through activation of endogenous enzymes

SG Nkhata, E Ayua, EH Kamau… - Food science & …, 2018 - Wiley Online Library
Cereals and legumes are outstanding sources of macronutrients, micronutrients,
phytochemicals, as well as antinutritional factors. These components present a complex …

[HTML][HTML] Secondary bile acids and short chain fatty acids in the colon: a focus on colonic microbiome, cell proliferation, inflammation, and cancer

H Zeng, S Umar, B Rust, D Lazarova… - International journal of …, 2019 - mdpi.com
Secondary bile acids (BAs) and short chain fatty acids (SCFAs), two major types of bacterial
metabolites in the colon, cause opposing effects on colonic inflammation at chronically high …

Nondigestible carbohydrates, butyrate, and butyrate-producing bacteria

X Fu, Z Liu, C Zhu, H Mou, Q Kong - Critical reviews in food science …, 2019 - Taylor & Francis
Nondigestible carbohydrates (NDCs) are fermentation substrates in the colon after escaping
digestion in the upper gastrointestinal tract. Among NDCs, resistant starch is not hydrolyzed …