[HTML][HTML] Current developments and future perspectives on biotechnology applications of natural deep eutectic systems

AR Jesus, A Paiva, ARC Duarte - Current Opinion in Green and …, 2023 - Elsevier
Abstract Natural Deep Eutectic Systems (NADES) have emerged in the past years as
alternative solvents to traditional organic solvents and ionic liquids. NADES are easy to …

Respiratory viruses and virus-like particle vaccine development: how far have we advanced?

KB Chu, FS Quan - Viruses, 2023 - mdpi.com
With technological advancements enabling globalization, the intercontinental transmission
of pathogens has become much easier. Respiratory viruses are one such group of …

Optimization of Deep Eutectic Solvents Enables Green and Efficient Cryopreservation

W He, T Zhan, H Han, Y Xu - Langmuir, 2023 - ACS Publications
Cryopreservation presents significant opportunities for biomedical applications including cell
therapy, tissue engineering, and assisted reproduction. Dimethyl sulfoxide (DMSO), the most …

Characterization of eutectic mixtures of sugars and sugar-alcohols for cryopreservation

A Joules, T Burrows, PI Dosa, A Hubel - Journal of molecular liquids, 2023 - Elsevier
Abstract Natural Deep Eutectic Systems (NADES) composed of sugar and sugar alcohols
have been studied and applied in a variety of biological applications. Understanding their …

[HTML][HTML] Viral protein nanoparticles (Part 1): Pharmaceutical characteristics

R Mellid-Carballal, S Gutierrez-Gutierrez… - European Journal of …, 2023 - Elsevier
Viral protein nanoparticles fill the gap between viruses and synthetic nanoparticles.
Combining advantageous properties of both systems, they have revolutionized …

Transcutaneous Immunization of 1D Rod-Like Tobacco-Mosaic-Virus-Based Peptide Vaccine via Tip-Loaded Dissolving Microneedles

J Ou, M Xing, G Lu, C Wan, K Li, W Jiang, W Qian… - Nano Letters, 2024 - ACS Publications
Peptide vaccines induce specific neutralizing antibodies and are effective in disease
prevention and treatment. However, peptide antigens have a low immunogenicity and are …

Study of Oncolytic Virus Preservation and Formulation

L Pan, X Liu, D Fan, Z Qian, X Sun, P Wu, L Zhong - Pharmaceuticals, 2023 - mdpi.com
In recent years, oncolytic viruses (OVs) have emerged as an effective means of treating
cancer. OVs have multiple oncotherapeutic functions including specifically infecting and …

Insect Cell-Based Quadrivalent Seasonal Influenza Virus-like Particles Vaccine Elicits Potent Immune Responses in Mice

ATM Badruzzaman, YC Cheng, WC Sung, MS Lee - Vaccines, 2024 - mdpi.com
Influenza viruses can cause highly infectious respiratory diseases, posing noteworthy
epidemic and pandemic threats. Vaccination is the most cost-effective intervention to prevent …

Targeted metabolic analysis and MFA of insect cells expressing influenza HA-VLP

AB Murad, MQ Sousa, R Correia, IA Isidro… - Processes, 2022 - mdpi.com
Virus-like particles (VLPs) are versatile vaccine carriers for conferring broad protection
against influenza by enabling high-level display of multiple hemagglutinin (HA) strains …

Biopolymers and Osmolytes—A Focus towards the Prospects of Stability and Adjuvanticity of Vaccines

K Athirathinam, S Nandakumar… - Macromolecular Research, 2022 - Springer
Abstract 'New-Gen Vaccines' are grabbing the attention of scientists as they are much
suitable for an immune-compromised group of individuals as well as infants. The major …