Frailty and heart failure: State‐of‐the‐art review

KM Talha, A Pandey, M Fudim, J Butler… - Journal of Cachexia …, 2023 - Wiley Online Library
At least half of all patients with heart failure (HF) are affected by frailty, a syndrome that limits
an individual ability to recover from acute stressors. While frailty affects up to 90% of patients …

[HTML][HTML] Frailty in aging and the search for the optimal biomarker: a review

M Sepúlveda, D Arauna, F García, C Albala, I Palomo… - Biomedicines, 2022 - mdpi.com
In the context of accelerated aging of the population worldwide, frailty has emerged as one
of the main risk factors that can lead to loss of self-sufficiency in older people. This syndrome …

The burden of frailty in heart failure: Prevalence, impacts on clinical outcomes and the role of heart failure medications

HY Lai, ST Huang, SD Anker… - Journal of cachexia …, 2024 - Wiley Online Library
Background Frailty often coexists with heart failure (HF), which significantly aggravates the
clinical outcomes of older adults. However, studies investigating the interplay between frailty …

The effect of frailty on the efficacy and safety of intensive blood pressure control: a post hoc analysis of the SPRINT trial

Z Wang, X Du, C Hua, W Li, H Zhang, X Liu, Y Wang… - Circulation, 2023 - Am Heart Assoc
BACKGROUND: Frailty is associated with an increased risk of all-cause death and
cardiovascular events. However, it is uncertain whether frailty modifies the efficacy and …

Effectiveness of supervised exercise, home-based exercise, or walk advice strategies on walking performance and muscle endurance in patients with intermittent …

A Sandberg, M Bäck, Å Cider, L Jivegård… - European Journal of …, 2023 - academic.oup.com
Aims Supervised exercise is a guideline-recommended treatment in intermittent claudication
(IC). Hospital-based supervised exercise programmes (SEPs) are underutilized, while home …

Cardiovascular vs. non‐cardiovascular deaths after heart failure hospitalization in young, older, and very old patients

R Nakamaru, Y Shiraishi, AT Sandhu… - ESC Heart …, 2023 - Wiley Online Library
Aims The long‐term outcome in patients with heart failure (HF) after hospitalization may vary
substantially depending on their age and left ventricular ejection fraction (LVEF). We aimed …

[HTML][HTML] Latest pharmaceutical approaches across the spectrum of heart failure

D Bismpos, J Wintrich, J Hövelmann, M Böhm - Heart Failure Reviews, 2024 - Springer
Despite major advances in prevention and medical therapy, heart failure (HF) remains
associated with high morbidity and mortality, especially in older and frailer patients …

Prevalence and prognosis of frailty in older patients with stage B heart failure with preserved ejection fraction

C Meng, K Chai, YY Li, Y Luo, H Wang… - ESC Heart …, 2023 - Wiley Online Library
Aims Frailty in older patients with stage B heart failure with preserved ejection fraction
(HFpEF) has not been fully explored. We evaluated the prevalence and prognostic …

Impact of Multidomain Frailty on the Mode of Death in Older Patients With Heart Failure: A Cohort Study

K Ohashi, Y Matsue, D Maeda, Y Fujimoto… - … Quality and Outcomes, 2024 - Am Heart Assoc
BACKGROUND: Although frailty is strongly associated with mortality in patients with heart
failure (HF), the risk of which specific cause of death is associated with being complicated …

Frailty is associated with 90-day unplanned readmissions and death in patients with heart failure: A longitudinal study in China

J Chi, F Chen, J Zhang, X Niu, H Tao, H Ruan, L Jin… - Heart & Lung, 2022 - Elsevier
Background Frailty has been reported to be significantly associated with adverse health
outcomes in people with heart failure (HF). Objectives To explore the potential effects of …