Myelinated nerve fibers are essential for the rapid propagation of action potentials by
saltatory conduction. They form as the result of reciprocal interactions between axons and …

Melanocyte development provides an excellent model for studying more complex
developmental processes. Melanocytes have an apparently simple aetiology, differentiating …

Oligodendrocytes, the myelin-forming glial cells of the central nervous system, maintain long-
term axonal integrity,,. However, the underlying support mechanisms are not understood …

Schwann cell precursors (SCPs) are nerve‐associated progenitors that can generate
myelinating and non‐myelinating Schwann cells but also are multipotent like the neural …

Across mammalian skin, structurally complex and diverse mechanosensory end organs
respond to mechanical stimuli and enable our perception of dynamic, light touch. How forces …

During the development of peripheral nerves, neural crest cells generate myelinating and
non-myelinating glial cells in a process that parallels gliogenesis from the germinal layers of …

Peripheral innervation plays an important role in regulating tissue repair and regeneration.
Here we provide evidence that injured peripheral nerves provide a reservoir of …

The peripheral nervous system harbors a remarkable potential to regenerate after acute
nerve trauma. Full functional recovery, however, is rare and critically depends on peripheral …

In the peripheral nervous system, Schwann cells are glial cells that are in intimate contact
with axons throughout development. Schwann cells generate the insulating myelin sheath …

Ablation of the cellular prion protein PrPC leads to a chronic demyelinating polyneuropathy
affecting Schwann cells. Neuron-restricted expression of PrPC prevents the disease …