Fimbriae are long filamentous polymeric protein structures located upon the surface of
bacteria. Often implicated in pathogenicity, the biosynthesis and function of fimbriae has …

In tissue engineering, the composition and the structural arrangement of molecular
components within the extracellular matrix (ECM) determine the physical and biochemical …

There is a growing realization that 3D cell culture better mimics complex in vivo
environments than 2D, lessening aberrant cellular behaviors and ultimately improving the …

Complex biomaterials easily formed by self-assembling proteins could transform
regenerative medicine and 3D cell culture. However, although readily achieved by short …

The pathogenic bacterium Yersina pestis is protected from macrophage engulfment by a
capsule like antigen, F1, formed of long polymers of the monomer protein, Caf1. However …

Chemically crosslinked hydrogels can be used for the controlled delivery of therapeutic
proteins, however, cargo loading can be challenging. A common approach involves …

Demand continues to grow for biomimetic materials able to create well-defined
environments for modulating the behaviour of living cells in culture. Here, we describe …

Background: Escherichia coli (E. coli) represent one of the major pathogens implicated in
catheter associated urinary tract infection (CAUTI). Formation of biofilm by uropathogenic E …

Induced pluripotent stem cells (iPSCs) are of significant value due to their wide ranging
potential, removing the need for embryonic material. To successfully culture, expand and …

Pathogenic bacteria such as Yersinia pestis, causative agent of the plague, have a genetic
armoury of proteins they use to defend themselves against the immune system when …