The cytoskeleton and its components—actin, microtubules and intermediate filaments—
have been studied for decades, and multiple roles of the individual cytoskeletal …

The mammalian lung´ s structural design is optimized to serve its main function: gas
exchange. It takes place in the alveolar region (parenchyma) where air and blood are …

Nanotopography presents an effective physical approach for biomaterial cell manipulation
mediated through material-extracellular matrix interactions. The extracellular matrix that …

Reactive oxygen species (ROS) are key signaling molecules that play an important role in
the progression of inflammatory disorders. An enhanced ROS generation by …

Stem cells respond to nanoscale surface features, with changes in cell growth and
differentiation mediated by alterations in cell adhesion. The interaction of nanotopographical …

Current measurements of the biomechanical properties of cells require physical contact with
cells or lack subcellular resolution. Here we developed a label-free microscopy technique …

The recent convergence between physics and biology has led many physicists to enter the
fields of cell and developmental biology. One of the most exciting areas of interest has been …

Cells within tissues are continuously exposed to physical forces including hydrostatic
pressure, shear stress, and compression and tension forces. Cells dynamically adapt to …

Tensegrity structures provide both structural integrity and flexibility through the combination
of stiff struts and a network of flexible tendons. These structures exhibit useful properties …

Research in cellular mechanotransduction often focuses on how extracellular physical
forces are converted into chemical signals at the cell surface. However, mechanical forces …