Virulence factors of the Mycobacterium tuberculosis complex
MA Forrellad, LI Klepp, A Gioffré, J Sabio y Garcia… - Virulence, 2013 - Taylor & Francis
The Mycobacterium tuberculosis complex (MTBC) consists of closely related species that
cause tuberculosis in both humans and animals. This illness, still today, remains to be one of …
cause tuberculosis in both humans and animals. This illness, still today, remains to be one of …
Transcriptional regulation by Ferric Uptake Regulator (Fur) in pathogenic bacteria
B Troxell, HM Hassan - Frontiers in cellular and infection microbiology, 2013 - frontiersin.org
In the ancient anaerobic environment, ferrous iron (Fe2+) was one of the first metal
cofactors. Oxygenation of the ancient world challenged bacteria to acquire the insoluble …
cofactors. Oxygenation of the ancient world challenged bacteria to acquire the insoluble …
How do bacterial cells ensure that metalloproteins get the correct metal?
KJ Waldron, NJ Robinson - Nature Reviews Microbiology, 2009 - nature.com
Protein metal-coordination sites are richly varied and exquisitely attuned to their inorganic
partners, yet many metalloproteins still select the wrong metals when presented with …
partners, yet many metalloproteins still select the wrong metals when presented with …
The FUR (ferric uptake regulator) superfamily: diversity and versatility of key transcriptional regulators
MF Fillat - Archives of biochemistry and biophysics, 2014 - Elsevier
Control of metal homeostasis is essential for life in all kingdoms. In most prokaryotic
organisms the FUR (ferric uptake regulator) family of transcriptional regulators is involved in …
organisms the FUR (ferric uptake regulator) family of transcriptional regulators is involved in …
Type VII secretion—mycobacteria show the way
AM Abdallah, NC Gey van Pittius… - Nature reviews …, 2007 - nature.com
Recent evidence shows that mycobacteria have developed novel and specialized secretion
systems for the transport of extracellular proteins across their hydrophobic, and highly …
systems for the transport of extracellular proteins across their hydrophobic, and highly …
Coordination chemistry of bacterial metal transport and sensing
Z Ma, FE Jacobsen, DP Giedroc - Chemical reviews, 2009 - ACS Publications
The transition or d-block metal ions manganese, iron, cobalt, nickel, copper, zinc and to a
more specialized degree molybdenum, tungsten, and vanadium have been shown to be …
more specialized degree molybdenum, tungsten, and vanadium have been shown to be …
Metal limitation and toxicity at the interface between host and pathogen
Metals are required cofactors for numerous fundamental processes that are essential to both
pathogen and host. They are coordinated in enzymes responsible for DNA replication and …
pathogen and host. They are coordinated in enzymes responsible for DNA replication and …
At the crossroads of bacterial metabolism and virulence factor synthesis in Staphylococci
GA Somerville, RA Proctor - Microbiology and Molecular Biology …, 2009 - Am Soc Microbiol
Bacteria live in environments that are subject to rapid changes in the availability of the
nutrients that are necessary to provide energy and biosynthetic intermediates for the …
nutrients that are necessary to provide energy and biosynthetic intermediates for the …
Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis
Mycobacterium marinum, a ubiquitous pathogen of fish and amphibia, is a near relative of
Mycobacterium tuberculosis, the etiologic agent of tuberculosis in humans. The genome of …
Mycobacterium tuberculosis, the etiologic agent of tuberculosis in humans. The genome of …
Separable roles for Mycobacterium tuberculosis ESX-3 effectors in iron acquisition and virulence
JAM Tufariello, JR Chapman… - Proceedings of the …, 2016 - National Acad Sciences
Mycobacterium tuberculosis (Mtb) encodes five type VII secretion systems (T7SS),
designated ESX-1–ESX-5, that are critical for growth and pathogenesis. The best …
designated ESX-1–ESX-5, that are critical for growth and pathogenesis. The best …