Antioxidant Polymers with Enhanced Neuroprotection Against Insulin Fibrillation
Lipoic acid (LA) and dihydrolipoic acid (DHLA) are well established antioxidants to
scavenge reactive oxygen species (ROS). However, they are carboxylates with≈ 4.7 pKa …
scavenge reactive oxygen species (ROS). However, they are carboxylates with≈ 4.7 pKa …
Inhibition mechanism of human insulin fibrillation by Bodipy carbon polymer dots and photothermal defibrillation effect of Bodipy carbon polymer dots modified by ThT
XY Liu, SC Du, SL Li, FL Jiang, P Jiang, Y Liu - Biophysical Chemistry, 2023 - Elsevier
Fibrillation process of human insulin (HI) is closely related to type 2 diabetes (T2D). In the
present work, Carbon Polymer Dots (CPDs) was synthesized by Bodipy to control the …
present work, Carbon Polymer Dots (CPDs) was synthesized by Bodipy to control the …
Dual Role of a Fluorescent Small Molecule as a Sensor and Inhibitor of Protein Fibrillation
Ordered fibrillar aggregates of proteins, called amyloids, are prevalent in several diseases
like Alzheimer's, Parkinson's, and Type II diabetes. The key challenge in the treatment of …
like Alzheimer's, Parkinson's, and Type II diabetes. The key challenge in the treatment of …
[HTML][HTML] Comparative study of high-resolution lysb29 (nε-myristoyl) des (b30) insulin structures display novel dynamic causal interrelations in monomeric-dimeric …
The treatment of insulin-dependent diabetes mellitus is characterized by artificial
supplementation of pancreatic β-cell ability to regulate sugar levels in the blood. Even …
supplementation of pancreatic β-cell ability to regulate sugar levels in the blood. Even …