Pulmonary Tuberculosis in Children: A Forgotten Disease?

U Pelosi, R Pintus, S Savasta, V Fanos - Microorganisms, 2023 - mdpi.com
Even today, tuberculosis in childhood is a disease that is often undiagnosed and
undertreated. In the absence of therapy with antituberculosis drugs, children in the first years …

Tuberculosis in childhood and adolescence: a view from different perspectives

TT Tahan, BMA Gabardo, AMO Rossoni - Jornal de pediatria, 2020 - SciELO Brasil
Objective To describe the epidemiological situation of tuberculosis in children under 19
years of age in Brazil and to review the latest publications on disease risk, diagnosis …

Oral swab specimens tested with Xpert MTB/RIF Ultra assay for diagnosis of pulmonary tuberculosis in children: a diagnostic accuracy study

H Cox, L Workman, L Bateman… - Clinical Infectious …, 2022 - academic.oup.com
Background Microbiologic diagnosis of childhood tuberculosis may be difficult. Oral swab
specimens are a potential noninvasive alternative to sputum specimens for diagnosis …

Xpert Ultra assay on stool to diagnose pulmonary tuberculosis in children

S Kabir, SMM Rahman, S Ahmed… - Clinical Infectious …, 2021 - academic.oup.com
Abstract Background The World Health Organization recommends the Xpert MTB/RIF Ultra
assay for diagnosing pulmonary tuberculosis (PTB) in children. Though stool is a potential …

Tuberculosis symptom screening for children and adolescents living with HIV in six high HIV/TB burden countries in Africa

B Vonasek, A Kay, T Devezin, JM Bacha, P Kazembe… - Aids, 2021 - journals.lww.com
Objectives: The WHO recommends that children and adolescents living with HIV (CALHIV)
complete TB symptom screening at every clinical encounter but evidence supporting this …

No extraction? No problem. Direct to PCR processing of tongue swabs for diagnosis of tuberculosis disease as an alternative to sputum collection

CL Ahls, D Emsweller, SJ Helfers, X Niu… - Microbiology …, 2024 - Am Soc Microbiol
Sputum collection and testing for tuberculosis (TB) have been problematic due to the
potential for aerosolization, difficulty in generating a quality sample, and complex DNA …

Stool-based Xpert MTB/RIF Ultra assay as a tool for detecting pulmonary tuberculosis in children with abnormal chest imaging: a prospective cohort study

X Liu, L Xia, B Song, H Wang, X Qian, J Wei, T Li, X Xi… - Journal of Infection, 2021 - Elsevier
Objectives To evaluate the diagnostic efficacy of stool-based Xpert MTB/RIF Ultra assay
versus other assays for the detection of paediatric pulmonary tuberculosis (PTB). Methods A …

Treatment options for children with multi-drug resistant tuberculosis

G Bossù, G Autore, L Bernardi… - Expert Review of …, 2023 - Taylor & Francis
Introduction According to the latest report from the World Health Organization (WHO),
approximately 10.0 million people fell ill with tuberculosis (TB) in 2020, 12% of which were …

Rendimiento del GeneXpert en el diagnóstico de tuberculosis pulmonar y extrapulmonar en la edad pediátrica

G Amaya, M Contrera, F Arrieta, A Montano… - Archivos de pediatría …, 2020 - scielo.edu.uy
Rendimiento del GeneXpert en el diagnóstico de tuberculosis pulmonar y extrapulmonar en
la edad pediátrica SciELO - Scientific Electronic Library Online vol.91 suppl.2 …

Achieving a “step change” in the tuberculosis epidemic through comprehensive community-wide intervention: a model-based analysis

S Shrestha, EA Kendall, R Chang, R Joseph, P Kasaie… - BMC medicine, 2021 - Springer
Background Global progress towards reducing tuberculosis (TB) incidence and mortality has
consistently lagged behind the World Health Organization targets leading to a perception …