Droplet-based microfluidics

T Moragues, D Arguijo, T Beneyton, C Modavi… - Nature Reviews …, 2023 - nature.com
Droplet-based microfluidic systems generate, manipulate and control sub-microlitre droplets
enclosed within an immiscible carrier fluid. Owing to a number of remarkable features, such …

Microfluidic formulation of topological hydrogels for microtissue engineering

KO Rojek, M Cwiklinska, J Kuczak… - Chemical …, 2022 - ACS Publications
Microfluidics has recently emerged as a powerful tool in generation of submillimeter-sized
cell aggregates capable of performing tissue-specific functions, so-called microtissues, for …

Advances in Spheroids and Organoids on a Chip

G Fang, YC Chen, H Lu, D Jin - Advanced Functional Materials, 2023 - Wiley Online Library
Multicellular spheroids and organoids are promising in vitro 3D models in personalized
medicine and drug screening. They replicate the structural and functional characteristics of …

[HTML][HTML] Alginate-metal cation interactions: Macromolecular approach

I Donati, BE Christensen - Carbohydrate Polymers, 2023 - Elsevier
Alginates are a broad family of linear (unbranched) polysaccharides derived from brown
seaweeds and some bacteria. Despite having only two monomers, ie β-d-mannuronate (M) …

Design of capillary microfluidics for spinning cell-laden microfibers

Y Yu, L Shang, J Guo, J Wang, Y Zhao - Nature Protocols, 2018 - nature.com
This protocol describes the design of capillary microfluidics for spinning bioactive (cell-
laden) microfibers for three-dimensional (3D) cell culture and tissue-engineering …

Designing biopolymer microgels to encapsulate, protect and deliver bioactive components: Physicochemical aspects

DJ McClements - Advances in Colloid and Interface Science, 2017 - Elsevier
Biopolymer microgels have considerable potential for their ability to encapsulate, protect,
and release bioactive components. Biopolymer microgels are small particles (typically 100 …

Biomimetic behaviors in hydrogel artificial cells through embedded organelles

ME Allen, JW Hindley, N O'Toole… - Proceedings of the …, 2023 - National Acad Sciences
Artificial cells are biomimetic structures formed from molecular building blocks that replicate
biological processes, behaviors, and architectures. Of these building blocks, hydrogels have …

Tunable fibrin-alginate interpenetrating network hydrogels to support cell spreading and network formation

CE Vorwald, T Gonzalez-Fernandez, S Joshee… - Acta biomaterialia, 2020 - Elsevier
Hydrogels are effective platforms for use as artificial extracellular matrices, cell carriers, and
to present bioactive cues. Two common natural polymers, fibrin and alginate, are broadly …

Three-dimensional (3D) printed microneedles for microencapsulated cell extrusion

C Farias, R Lyman, C Hemingway, H Chau, A Mahacek… - Bioengineering, 2018 - mdpi.com
Cell-hydrogel based therapies offer great promise for wound healing. The specific aim of this
study was to assess the viability of human hepatocellular carcinoma (HepG2) cells …

Cytoprotection of human progenitor and stem cells through encapsulation in alginate templated, dual crosslinked silk and silk–gelatin composite hydrogel microbeads

O Hasturk, JA Smiley, M Arnett… - Advanced …, 2022 - Wiley Online Library
Susceptibility of mammalian cells against harsh processing conditions limit their use in cell
transplantation and tissue engineering applications. Besides modulation of the cell …