Therapeutic applications of curcumin in diabetes: a review and perspective

C Quispe, J Herrera-Bravo, Z Javed… - BioMed Research …, 2022 - Wiley Online Library
Diabetes is a metabolic disease with multifactorial causes which requires lifelong drug
therapy as well as lifestyle changes. There is now growing scientific evidence to support the …

Nanocurcumin: A promising candidate for therapeutic applications

A Karthikeyan, N Senthil, T Min - Frontiers in Pharmacology, 2020 - frontiersin.org
Curcuma longa is an important medicinal plant and a spice in Asia. Curcumin
(diferuloylmethane) is a hydrophobic bioactive ingredient found in a rhizome of the C. longa …

Biomedical applications and bioavailability of curcumin—An updated overview

SI Sohn, A Priya, B Balasubramaniam… - Pharmaceutics, 2021 - mdpi.com
Curcumin, a yellow-colored molecule derived from the rhizome of Curcuma longa, has been
identified as the bioactive compound responsible for numerous pharmacological activities of …

Curcumin and type 2 diabetes mellitus: prevention and treatment

F Pivari, A Mingione, C Brasacchio, L Soldati - Nutrients, 2019 - mdpi.com
Type 2 diabetes mellitus (T2DM) is an ensemble of metabolic diseases that has reached
pandemic dimensions all over the world. The multifactorial nature of the pathology makes …

Curcumin attenuates ferroptosis‐induced myocardial injury in diabetic cardiomyopathy through the Nrf2 pathway

Z Wei, Q Shaohuan, K Pinfang… - Cardiovascular …, 2022 - Wiley Online Library
Diabetes causes lipid peroxide to accumulate within cardiomyocytes. Furthermore, lipid
peroxide buildup is a risk factor for ferroptosis. This study is aimed at examining whether …

Regulation of toll-like receptor (TLR) signaling pathway by polyphenols in the treatment of age-linked neurodegenerative diseases: focus on TLR4 signaling

S Azam, M Jakaria, IS Kim, J Kim, ME Haque… - Frontiers in …, 2019 - frontiersin.org
Neuronal dysfunction initiates several intracellular signaling cascades to release different
proinflammatory cytokines and chemokines, as well as various reactive oxygen species. In …

Curcumin activates the Nrf2 pathway and induces cellular protection against oxidative injury

M Ashrafizadeh, Z Ahmadi… - Current Molecular …, 2020 - ingentaconnect.com
Curcumin is a naturally occurring polyphenol that is isolated from the rhizome of Curcuma
longa (turmeric). This medicinal compound has different biological activities, including …

Food polyphenols and type II diabetes mellitus: pharmacology and mechanisms

R Naz, F Saqib, S Awadallah, M Wahid, MF Latif, I Iqbal… - Molecules, 2023 - mdpi.com
Type II diabetes mellitus and its related complications are growing public health problems.
Many natural products present in our diet, including polyphenols, can be used in treating …

[HTML][HTML] Health benefits, extraction and development of functional foods with curcuminoids

PES Munekata, M Pateiro, W Zhang… - Journal of Functional …, 2021 - Elsevier
Turmeric (Curcuma longa) is an important condiment used in the culinary of several
countries to spice and give a more intense yellow color to food. The importance of this root …

[HTML][HTML] An investigation into the potential action of polyphenols against human Islet Amyloid Polypeptide aggregation in type 2 diabetes

A Mahboob, DKL Senevirathne, P Paul, F Nabi… - International Journal of …, 2023 - Elsevier
Abstract Type 2 diabetes (T2D), a chronic metabolic disease characterized by
hyperglycemia, results in significant disease burden and financial costs globally. Whilst the …