The world's big rivers and their floodplains were central to development of civilization and
are now home to c. 2.7 billion people. They are economically vital whilst also constituting …

Cancer therapy, even when highly targeted, typically fails because of the remarkable
capacity of malignant cells to evolve effective adaptations. These evolutionary dynamics are …

The natural flow regime concept has contributed significantly to environmental flows (e‐
flows) science and applications over the last 20 years. Natural flow regimes reflect long …

The term “environmental flows” describes the quantities, quality, and patterns of water flows
required to sustain freshwater and estuarine ecosystems and the ecosystem services they …

The science and practice of environmental flows have advanced significantly over the last
several decades. Most environmental flow approaches require quantifying the relationships …

The implementation of environmental flow regimes offers a promising means to protect and
restore riverine, wetland and estuarine ecosystems, their critical environmental services and …

Environmental flows assessment science focuses largely on defining how modified flow
regimes (from water infrastructure and direct water abstraction) can be managed to conserve …

Empirical relationships between stream flow and ecological responses (flow–ecology
relationships) are essential for establishing environmental flows and evaluating tradeoffs …

The term “environmental flows” is now widely used to reflect the hydrological regime
required to sustain freshwater and estuarine ecosystems, and the human livelihoods and …

Although it is widely acknowledged as a fundamental principle that models be fit-for-
purpose, there remains lack of clarity on what this notion actually means and therefore how it …