The Yin and Yang of exosome isolation methods: conventional practice, microfluidics, and commercial kits

SZ Shirejini, F Inci - Biotechnology Advances, 2022 - Elsevier
Exosomes are a subset of extracellular vesicles released from various cells, and they can be
found in different bodily fluids. Exosomes have been utilized as biomarkers to diagnose …

Carbon‐based nanomaterials and sensing tools for wearable health monitoring devices

Ö Erdem, E Derin, S Zeibi Shirejini… - Advanced Materials …, 2022 - Wiley Online Library
The healthcare system has a drastic paradigm shift from centralized care to home‐based
and self‐monitoring strategies; aiming to reach more individuals, minimize workload in …

In situ synthesis and dynamic simulation of molecularly imprinted polymeric nanoparticles on a micro-reactor system

Ö Erdem, I Eş, Y Saylan, M Atabay, MA Gungen… - Nature …, 2023 - nature.com
Current practices in synthesizing molecularly imprinted polymers face challenges—lengthy
process, low-productivity, the need for expensive and sophisticated equipment, and they …

Recent advances in microneedle-based sensors for sampling, diagnosis and monitoring of chronic diseases

Ö Erdem, I Eş, GA Akceoglu, Y Saylan, F Inci - Biosensors, 2021 - mdpi.com
Chronic diseases (CDs) are noncommunicable illnesses with long-term symptoms
accounting for~ 70% of all deaths worldwide. For the diagnosis and prognosis of CDs …

Simulating nature in sperm selection for assisted reproduction

ETY Leung, CL Lee, X Tian, KKW Lam, RHW Li… - Nature Reviews …, 2022 - nature.com
Sperm selection in the female reproductive tract (FRT) is sophisticated. Only about 1,000
sperm out of millions in an ejaculate reach the fallopian tube and thus have a chance of …

Microneedle technology as a new standpoint in agriculture: Treatment and sensing

E Ece, I Eş, F Inci - Materials Today, 2023 - Elsevier
Preventing plant loss and improving their health status are essential for agricultural industry.
Correspondingly, the deprivation of plants severely impacts our ecological system. As such …

A snapshot of microfluidics in point‐of‐care diagnostics: multifaceted integrity with materials and sensors

GA Akceoglu, Y Saylan, F Inci - Advanced Materials …, 2021 - Wiley Online Library
Over four decades, point‐of‐care (POC) technologies and their pivotal applications in the
biomedical arena have increased irrepressibly and allowed to realize the potential of …

A disposable microfluidic-integrated hand-held plasmonic platform for protein detection

F Inci, Y Saylan, AM Kojouri, MG Ogut, A Denizli… - Applied Materials …, 2020 - Elsevier
Healthcare is in the midst of a transformative shift from centralized care to point-of-care
(POC). In this regard, recent efforts have focused on integration of biosensing technologies …

Biosensors as nano-analytical tools for COVID-19 detection

A Pradhan, P Lahare, P Sinha, N Singh, B Gupta… - Sensors, 2021 - mdpi.com
Selective, sensitive and affordable techniques to detect disease and underlying health
issues have been developed recently. Biosensors as nanoanalytical tools have taken a front …

Advances in biosensor technologies for acute kidney injury

E Derin, F Inci - ACS sensors, 2021 - ACS Publications
Acute kidney injury (AKI) is one of the most prevalent and complex clinical syndromes with
high morbidity and mortality. The traditional diagnosis parameters are insufficient regarding …