Slster-chromatid exchanges (SCEs) represent the interchange of DNA replication products
at apparently homologous loci. The exchange process presumably involves DNA breakage …

Clinical animal cytogenetics development began in the 1960's, almost at the same time as
human cytogenetics. However, the development of the two disciplines has been very …

RANDOM X inactivation makes the female mammal a natural mosaic for clones of cells
having either the maternally derived X (Xm) or paternally derived one (Xp) which is …

We are reporting a male patient who suffered from chronic granulomatous disease
associated with cytochrome b− 245 deficiency and McLeod red cell phenotype, Duchenne …

Complete or 'true'hydatidiform mole, an abnormality of human gestation, is characterized by
hydropic degeneration of all placental villi, marked hypertrophy of the trophoblast, absence …

Expression of imprinted genes is dependent on their parental origin. This is reflected in the
heritable differential methylation of parental alleles. The gametic imprints are however …

We have made a detailed study of the X-chromosome replication pattern during the period
when X-inactivation is occurring in the mouse embryo. Our observations show unequivocal …

Bromodeoxyuridine (BrdUrd), a thymidine analogue incorporated into DNA, can be
quantified by fluorescent or chromophoric quenching of dyes bound to DNA or with …

A review is given of the incidence, cytogenetics, and biologic relevance of pericentric
inversions (pii). In 251 cases in the literature and our patients, 96 different inversion forms …

High-resolution chromosome analysis and multiple banding techniques were performed on
blood samples from 40 patients with Prader-Willi syndrome (PWS) as a follow-up to our …