[HTML][HTML] Emerging therapeutic strategies to overcome drug resistance in cancer cells

P Garg, J Malhotra, P Kulkarni, D Horne, R Salgia… - Cancers, 2024 - mdpi.com
Simple Summary This review explores the challenges of drug resistance in cancer treatment
and discusses innovative strategies to overcome them. Researchers aim to understand how …

Advancements in solid lipid nanoparticles and nanostructured lipid carriers for breast cancer therapy

H Marwah, HK Dewangan - Current pharmaceutical design, 2024 - benthamdirect.com
Solid Lipid Nanocarriers (SLNs) offer a promising avenue for breast cancer treatment, a
disease that accounts for 12.5% of global cancer cases. Despite strides in combined …

Long non-coding RNAs in drug resistance across the top five cancers: Update on their roles and mechanisms

Y Shi, J Adu-Amankwaah, Q Zhao, X Li, Q Yu, A Bushi… - Heliyon, 2024 - cell.com
Cancer drug resistance stands as a formidable obstacle in the relentless fight against the top
five prevalent cancers: breast, lung, colorectal, prostate, and gastric cancers. These …

[HTML][HTML] Resistance mechanisms and prospects of trastuzumab

L Wang, Y Wang, Y Li, L Zhou, J Du… - Frontiers in …, 2024 - pmc.ncbi.nlm.nih.gov
Breast cancer that overexpresses Human Epidermal Growth Factor Receptor 2 (HER2+) due
to gene amplification or overexpression constitutes 15-20% of all breast cancer cases …

Targeted Sequencing of HER2-Positive Breast Cancer Mutations Revealed a Potential Association between PIK3CA and Trastuzumab Resistance

AM Mekhamer, MH Saied, DAE Elneily… - Asian Pacific Journal …, 2024 - journal.waocp.org
Background: Different molecular subtypes, including HER2-positive, have been identified in
breast cancer. The overexpression of HER2 triggers downstream signaling pathways such …

抗人表皮生长因子受体2 抗体药物偶联物在人表皮生长因子受体2 低表达泛瘤种中的治疗进展.

危彤, 袁芃 - Chinese Journal of Oncology, 2024 - search.ebscohost.com
抗体药物偶联物(ADCs) 由靶向特异性抗原的单克隆抗体药物和小分子细胞毒药物通过连接子偶
联而成, 它结合了高特异性靶向能力和强效杀伤作用的优势, 实现了对癌细胞的精准高效打击 …

[PDF][PDF] Insight into Estrogen Receptor Inhibitory Activity of Zingiber officinale-Derived Compounds: in silico Studies

OO Elekofehinti, FO Ayodeji, IR Adetoyi, FA Taiwo… - 2024 - nanobioletters.com
Breast cancer is one of the most commonly diagnosed forms of the disease, and it is also the
leading cause of cancer-related deaths among women worldwide. One of the most important …

Devising Breast Cancer Diagnosis Protocol through Machine Learning

T Mujtaba - 2024 - preprints.org
Breast cancer is a multifaceted disease that has many subcategories characterized by
unique genetic features. This research focuses on two important subgroups, including ER+ …

Enhancing Tumoricidal Effects of Radiation Therapy With Low-Intensity Focused Ultrasound in Murine Breast Cancers

MM Schumacher - 2023 - search.proquest.com
While local therapeutic treatments for cancer effectively eradicate primary tumor tissue, they
are rarely successful in suppressing metastatic disease. Our previous research has …