Intelligent poly (l-histidine)-based nanovehicles for controlled drug delivery
Stimuli-responsive drug delivery systems based on polymeric nanovehicles are among the
most promising treatment regimens for malignant cancers. Such intelligent systems that …
most promising treatment regimens for malignant cancers. Such intelligent systems that …
Host defense peptide mimicking antimicrobial amino acid polymers and beyond: Design, synthesis and biomedical applications
Microbial infections endanger human health and life. Conventional antibiotics has saved
countless human lives, however, is seriously challenged by the quick emergence of …
countless human lives, however, is seriously challenged by the quick emergence of …
Beyond nylon 6: Polyamides via ring opening polymerization of designer lactam monomers for biomedical applications
M Varghese, MW Grinstaff - Chemical Society Reviews, 2022 - pubs.rsc.org
Ring opening polymerization (ROP) of lactams is a highly efficient and versatile method to
synthesize polyamides. Within the last ten years, significant advances in polymerization …
synthesize polyamides. Within the last ten years, significant advances in polymerization …
[HTML][HTML] Membrane-disruptive peptides/peptidomimetics-based therapeutics: Promising systems to combat bacteria and cancer in the drug-resistant era
L Lin, J Chi, Y Yan, R Luo, X Feng, Y Zheng… - … Pharmaceutica Sinica B, 2021 - Elsevier
Membrane-disruptive peptides/peptidomimetics (MDPs) are antimicrobials or
anticarcinogens that present a general killing mechanism through the physical disruption of …
anticarcinogens that present a general killing mechanism through the physical disruption of …
Peptide Polymer‐Doped Cement Acting as an Effective Treatment of MRSA‐Infected Chronic Osteomyelitis
Chronic osteomyelitis is a painful and serious disease normally caused by infected surgical
prostheses or infected fractures. Currently, antibiotic‐loaded cements are extensively used …
prostheses or infected fractures. Currently, antibiotic‐loaded cements are extensively used …
Polypeptides–drug conjugates for anticancer therapy
Polypeptides are an important class of biodegradable polymers that have been widely used
in drug delivery field. Owing to the controllable synthesis and robust side chain …
in drug delivery field. Owing to the controllable synthesis and robust side chain …
Microbial Metabolite Inspired β‐Peptide Polymers Displaying Potent and Selective Antifungal Activity
D Zhang, C Shi, Z Cong, Q Chen, Y Bi… - Advanced …, 2022 - Wiley Online Library
Potent and selective antifungal agents are urgently needed due to the quick increase of
serious invasive fungal infections and the limited antifungal drugs available. Microbial …
serious invasive fungal infections and the limited antifungal drugs available. Microbial …
An effective strategy to develop potent and selective antifungal agents from cell penetrating peptides in tackling drug-resistant invasive fungal infections
The high mortality rate of invasive fungal infections and quick emergence of drug-resistant
fungal pathogens urgently call for potent antifungal agents. Inspired by the cell penetrating …
fungal pathogens urgently call for potent antifungal agents. Inspired by the cell penetrating …
A natural polyphenol-functionalized chitosan/gelatin sponge for accelerating hemostasis and infected wound healing
Y Sun, T Miao, Y Wang, X Wang, J Lin, N Zhao… - Biomaterials …, 2023 - pubs.rsc.org
Natural polymers have been particularly appealing for constructing hemostatic
materials/devices, but it is still desirable to develop new natural polymer-based biomaterials …
materials/devices, but it is still desirable to develop new natural polymer-based biomaterials …
Switching from membrane disrupting to membrane crossing, an effective strategy in designing antibacterial polypeptide
Drug-resistant bacterial infections have caused serious threats to human health and call for
effective antibacterial agents that have low propensity to induce antimicrobial resistance …
effective antibacterial agents that have low propensity to induce antimicrobial resistance …