The parasubiculum is a major input structure of layer 2 of medial entorhinal cortex, where
most grid cells are found. Here we investigated parasubicular circuits of the rat by …

Background Two decades of human neuroimaging research have associated volume
reductions in the hippocampus with posttraumatic stress disorder. However, little is known …

Acetylcholine (ACh) is a regulator of neural excitability and one of the neurochemical
substrates of sleep. Amongst the cellular effects induced by cholinergic modulation are a …

Presynaptic modulation has been associated mainly with calcium channels but recent data
suggests that inward rectifier potassium channels (KIR) also play a role. In this work we set …

Neurons in the superficial layers of the entorhinal cortex provide the hippocampus with the
majority of its cortical sensory input, and also receive the major output projection from the …

Phosphoinositides (PIs) are minor constituents of eukaryotic membranes that control a
plethora of cellular functions through direct modulation of membrane-associated proteins …

Temporal lobe epilepsy (TLE) is the commonest of adult epilepsies, often refractory to
antiepileptic medications, whose prevention and treatment rely on understanding basic …

Temporal lobe epilepsy (TLE) is the commonest of adult epilepsies, often refractory to
antiepileptic medications, whose prevention and treatment rely on understanding basic …

The ability of the mammalian brain to maintain spatial representations of external or internal
information for short periods of time has been associated with sustained neuronal spiking …

The superficial layers of the entorhinal cortex receive sensory and associational cortical
inputs and provide the hippocampus with the majority of its cortical sensory input. The …