CD38 is a molecule that can act as an enzyme, with NAD-depleting and intracellular
signaling activity, or as a receptor with adhesive functions. CD38 can be found expressed …

The emerging links between our gut microbiome and the central nervous system are
regarded as a paradigm shift in neuroscience with possible implications for not only …

The intestinal mucosa exists in dynamic balance with trillions of luminal microbes. Disruption
of the intestinal epithelial barrier, commonly observed in mucosal inflammation and …

Advanced age is associated with chronic low-grade inflammation, which is usually referred
to as inflammaging. Elderly are also known to have an altered gut microbiota composition …

Colon targeted drug delivery is an active area of research for local diseases affecting the
colon, as it improves the efficacy of therapeutics and enables localized treatment, which …

The intestinal epithelium is a single-cell layer that constitutes the largest and most important
barrier against the external environment. It acts as a selectively permeable barrier …

Most, if not all, animals coexist with a complement of prokaryotic symbionts that confer a
variety of physiologic benefits. In humans, the interaction between animal and bacterial cells …

Background and objective: Inflammatory bowel disease (IBD), including Crohn's disease
and ulcerative colitis, is a chronic inflammatory disorder characterized by aberrant immune …

Inflammatory bowel disease (IBD) is a lifelong chronic inflammation of the gastrointestinal
tract. Polysaccharides from mushrooms have been extensively used to treat inflammatory …

Background The gut microflora in some patients with Crohn's disease can be reduced in
numbers of butyrate-producing bacteria and this could result in metabolic stress in the …