[HTML][HTML] The pipeline for drugs for control and elimination of neglected tropical diseases: 1. Anti-infective drugs for regulatory registration
KM Pfarr, AK Krome, I Al-Obaidi, H Batchelor… - Parasites & …, 2023 - Springer
Abstract The World Health Organization 'Ending the neglect to attain the Sustainable
Development Goals: A road map for neglected tropical diseases 2021–2030'outlines the …
Development Goals: A road map for neglected tropical diseases 2021–2030'outlines the …
[HTML][HTML] Integrated management of skin NTDs—lessons learned from existing practice and field research
RR Yotsu - Tropical medicine and infectious disease, 2018 - mdpi.com
Integration of neglected tropical diseases (NTDs) into the public health agenda has been a
priority in global health for the last decade. Because a number of these diseases share not …
priority in global health for the last decade. Because a number of these diseases share not …
[HTML][HTML] Yaws re-emergence and bacterial drug resistance selection after mass administration of azithromycin: a genomic epidemiology investigation
MA Beale, M Noguera-Julian, C Godornes… - The Lancet …, 2020 - thelancet.com
Background In a longitudinal study assessing the WHO strategy for yaws eradication using
mass azithromycin treatment, we observed resurgence of yaws cases with dominance of a …
mass azithromycin treatment, we observed resurgence of yaws cases with dominance of a …
[HTML][HTML] Detection of cutaneous leishmaniasis in three communities of Oti Region, Ghana
R Akuffo, C Sanchez, C Chicharro… - PLoS Neglected …, 2021 - journals.plos.org
Background Cutaneous leishmaniasis (CL) is the most common type of leishmaniasis, a
neglected tropical disease caused by parasites of the genus Leishmania. In Ghana, some …
neglected tropical disease caused by parasites of the genus Leishmania. In Ghana, some …
[HTML][HTML] Plau and Tgfbr3 are YAP-regulated genes that promote keratinocyte proliferation
SM Corley, V Mendoza-Reinoso, N Giles… - Cell Death & …, 2018 - nature.com
Yes-associated protein (YAP) is a mechanosensor protein and a downstream effector of the
Hippo kinase pathway, which controls organ growth, cell proliferation, survival, maintenance …
Hippo kinase pathway, which controls organ growth, cell proliferation, survival, maintenance …
[HTML][HTML] Multiplex mediator displacement loop-mediated isothermal amplification for detection of treponema pallidum and haemophilus ducreyi
L Becherer, S Knauf, M Marks, S Lueert… - Emerging infectious …, 2020 - ncbi.nlm.nih.gov
Yaws, a neglected tropical disease caused by the bacterium Treponema pallidum
subspecies pertenue, manifests as ulcerative skin lesions. Nucleic acid amplification tests …
subspecies pertenue, manifests as ulcerative skin lesions. Nucleic acid amplification tests …
[HTML][HTML] Endemic infectious cutaneous ulcers syndrome in the Oti Region of Ghana: Study of cutaneous leishmaniasis, yaws and Haemophilus ducreyi cutaneous …
RA Akuffo, C Sanchez, I Amanor, JS Amedior… - Plos one, 2023 - journals.plos.org
Background A recent study detected cutaneous leishmaniasis (CL) in 31.9% of persons with
skin ulcers in the Oti Region of Ghana, resulting in a need to investigate other potential …
skin ulcers in the Oti Region of Ghana, resulting in a need to investigate other potential …
[HTML][HTML] Coinfection of a yaws patient with two closely related Treponema pallidum subsp. pertenue strains: A rare event with potential evolutionary implications
M Medappa, P Pospíšilová, LN John… - Acta Tropica, 2024 - Elsevier
The etiological agent of yaws is the spirochete Treponema pallidum (TP) subsp. pertenue
(TPE) and infects the children of Papua New Guinea, causing ulcerative skin lesions that …
(TPE) and infects the children of Papua New Guinea, causing ulcerative skin lesions that …
[HTML][HTML] Epidemiologic and genomic reidentification of yaws, Liberia
JWS Timothy, MA Beale, E Rogers… - Emerging Infectious …, 2021 - ncbi.nlm.nih.gov
We confirmed endemicity and autochthonous transmission of yaws in Liberia after a
population-based, community-led burden estimation (56,825 participants). Serologically …
population-based, community-led burden estimation (56,825 participants). Serologically …
[HTML][HTML] A Loop-Mediated Isothermal Amplification Assay for the Detection of Treponema pallidum subsp. pertenue
LAW Basing, SV Simpson, Y Adu-Sarkodie… - The American journal …, 2020 - ncbi.nlm.nih.gov
The eradication of yaws caused by Treponema pallidum subsp. pertenue is constrained by
the lack of rapid, accurate diagnosis. We sought to develop a molecular point-of-care test for …
the lack of rapid, accurate diagnosis. We sought to develop a molecular point-of-care test for …