Global epidemiology, health burden and effective interventions for elevated blood pressure and hypertension
High blood pressure is one of the most important risk factors for ischaemic heart disease,
stroke, other cardiovascular diseases, chronic kidney disease and dementia. Mean blood …
stroke, other cardiovascular diseases, chronic kidney disease and dementia. Mean blood …
Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease
Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …
NCD Countdown 2030: worldwide trends in non-communicable disease mortality and progress towards Sustainable Development Goal target 3.4
Summary The third UN High-Level Meeting on Non-Communicable Diseases (NCDs) on
Sept 27, 2018, will review national and global progress towards the prevention and control …
Sept 27, 2018, will review national and global progress towards the prevention and control …
Hypertension-induced cognitive impairment: from pathophysiology to public health
Hypertension affects two-thirds of people aged> 60 years and significantly increases the risk
of both vascular cognitive impairment and Alzheimer's disease. Hypertension compromises …
of both vascular cognitive impairment and Alzheimer's disease. Hypertension compromises …
Defining the relationship between hypertension, cognitive decline, and dementia: a review
KA Walker, MC Power, RF Gottesman - Current hypertension reports, 2017 - Springer
Hypertension is a highly prevalent condition which has been established as a risk factor for
cardiovascular and cerebrovascular disease. Although the understanding of the relationship …
cardiovascular and cerebrovascular disease. Although the understanding of the relationship …
[HTML][HTML] Pathophysiologic relationship between Alzheimer's disease, cerebrovascular disease, and cardiovascular risk: a review and synthesis
As the population ages due to demographic trends and gains in life expectancy, the
incidence and prevalence of dementia increases, and the need to understand the etiology …
incidence and prevalence of dementia increases, and the need to understand the etiology …
Preventing dementia by preventing stroke: the Berlin Manifesto
V Hachinski, K Einhäupl, D Ganten, S Alladi… - Alzheimer's & …, 2019 - Elsevier
The incidence of stroke and dementia are diverging across the world, rising for those in low-
and middle-income countries and falling in those in high-income countries. This suggests …
and middle-income countries and falling in those in high-income countries. This suggests …
Brain structure and cognitive ability in healthy aging: a review on longitudinal correlated change
Little is still known about the neuroanatomical substrates related to changes in specific
cognitive abilities in the course of healthy aging, and the existing evidence is predominantly …
cognitive abilities in the course of healthy aging, and the existing evidence is predominantly …
The projected effect of risk factor reduction on Alzheimer's disease prevalence
Summary At present, about 33· 9 million people worldwide have Alzheimer's disease (AD),
and prevalence is expected to triple over the next 40 years. The aim of this Review was to …
and prevalence is expected to triple over the next 40 years. The aim of this Review was to …
A major mechanism for immunomodulation: Dietary fibres and acid metabolites
Diet and the gut microbiota have a profound influence on physiology and health, however,
mechanisms are still emerging. Here we outline several pathways that gut microbiota …
mechanisms are still emerging. Here we outline several pathways that gut microbiota …