Knowledge discovery in medicine: Current issue and future trend
N Esfandiari, MR Babavalian, AME Moghadam… - Expert Systems with …, 2014 - Elsevier
Data mining is a powerful method to extract knowledge from data. Raw data faces various
challenges that make traditional method improper for knowledge extraction. Data mining is …
challenges that make traditional method improper for knowledge extraction. Data mining is …
[HTML][HTML] Data mining in healthcare: Applying strategic intelligence techniques to depict 25 years of research development
In order to identify the strategic topics and the thematic evolution structure of data mining
applied to healthcare, in this paper, a bibliometric performance and network analysis …
applied to healthcare, in this paper, a bibliometric performance and network analysis …
Model‐guided microarray implicates the retromer complex in Alzheimer's disease
SA Small, K Kent, A Pierce, C Leung… - Annals of Neurology …, 2005 - Wiley Online Library
Although, in principle, gene expression profiling is well suited to isolate pathogenic
molecules associated with Alzheimer's disease (AD), techniques such as microarray present …
molecules associated with Alzheimer's disease (AD), techniques such as microarray present …
ABCG2 is upregulated in Alzheimer's brain with cerebral amyloid angiopathy and may act as a gatekeeper at the blood–brain barrier for Aβ1–40 peptides
H Xiong, D Callaghan, A Jones, J Bai… - Journal of …, 2009 - Soc Neuroscience
Alzheimer's disease (AD) is characterized by accumulation and deposition of Aβ peptides in
the brain. Aβ deposition in cerebrovessels occurs in many AD patients and results in …
the brain. Aβ deposition in cerebrovessels occurs in many AD patients and results in …
Knowledge and intelligent computing system in medicine
B Pandey, RB Mishra - Computers in biology and medicine, 2009 - Elsevier
Knowledge-based systems (KBS) and intelligent computing systems have been used in the
medical planning, diagnosis and treatment. The KBS consists of rule-based reasoning …
medical planning, diagnosis and treatment. The KBS consists of rule-based reasoning …
[HTML][HTML] Sex of the cell dictates its response: differential gene expression and sensitivity to cell death inducing stress in male and female cells
C Penaloza, B Estevez, S Orlanski, M Sikorska… - The FASEB …, 2009 - ncbi.nlm.nih.gov
Sexual dimorphisms are typically attributed to the hormonal differences arising once sex
differentiation has occurred. However, in some sexually dimorphic diseases that differ in …
differentiation has occurred. However, in some sexually dimorphic diseases that differ in …
Pharmacogenomics in Alzheimer's disease
R Cacabelos - … in Drug Discovery and Development: From Bench to …, 2008 - Springer
Pharmacological treatment in Alzheimer's disease (AD) accounts for 10–20% of direct costs,
and fewer than 20% of AD patients are moderate responders to conventional drugs …
and fewer than 20% of AD patients are moderate responders to conventional drugs …
[HTML][HTML] A computational analysis of protein-protein interaction networks in neurodegenerative diseases
Background Recent developments have meant that network theory is making an important
contribution to the topological study of biological networks, such as protein-protein …
contribution to the topological study of biological networks, such as protein-protein …
Dissecting complex and multifactorial nature of Alzheimer's disease pathogenesis: a clinical, genomic, and systems biology perspective
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by loss
of memory and other cognitive functions. AD can be classified into familial AD (FAD) and …
of memory and other cognitive functions. AD can be classified into familial AD (FAD) and …
[HTML][HTML] Common transcriptional signatures in brain tissue from patients with HIV-associated neurocognitive disorders, Alzheimer's disease, and Multiple Sclerosis
A Borjabad, DJ Volsky - Journal of Neuroimmune Pharmacology, 2012 - Springer
Abstract HIV-Associated Neurocognitive Disorders (HAND) is a common manifestation of
HIV infection that afflicts about 50% of HIV-positive individuals. As people with access to …
HIV infection that afflicts about 50% of HIV-positive individuals. As people with access to …